.... Published by The Company of Biologists Ltd 2014 Otic specification Morphogenesis Sensory patch Maculae Cristae Semicircular canals Endolymphatic system Tegmentum vasculosum Compartment Cell lineage Modeling any developing organ of an organism is an attempt to rationally systematize...

...Isabelle Becam; Neus Rafel; Xin Hong; Stephen M. Cohen; Marco Milán Subdivision of proliferating tissues into adjacent compartments that do not mix plays a key role in animal development. The Actin cytoskeleton has recently been shown to mediate cell sorting at compartment boundaries, and reduced...

...N. Abimbola Sunmonu; Kairong Li; Qiuxia Guo; James Y. H. Li In vertebrates, the common expression border of two homeobox genes, Otx2 and Gbx2 , demarcates the prospective midbrain-hindbrain border (MHB) in the neural plate at the end of gastrulation. The presence of a compartment boundary...

... to be able to cross rhombomeric or the pallial-subpallial boundaries, although their progenitors in the proliferating zone are restricted to a cell-tight compartment ( Fishell et al.,1993 ; Wingate and Lumsden,1996 ). It has been postulated that compartmental boundaries are mainly required...

...Robert J. Major; Kenneth D. Irvine Compartment boundaries play key roles in tissue organization by separating cell populations. Activation of the Notch receptor is required for dorsoventral (DV) compartmentalization of the Drosophila wing, but the nature of its requirement has been controversial...

... some aspects of dorsal affinity on ventral cells, but loss of both molecules does not cause dorsal cells to cross into the ventral compartment ( Milan et al., 2001 ); thus, if these proteins are involved in compartmentalization they must be redundant with other signals. We considered the possibility...

...Peter A. Lawrence; José Casal; Gary Struhl The abdomen of adult Drosophila consists of a chain of alternating anterior (A) and posterior (P) compartments which are themselves subdivided into stripes of different types of cuticle. Most of the cuticle is decorated with hairs and bristles that point...

...Motoyuki Itoh; Tetsuhiro Kudoh; Michael Dedekian; Cheol-Hee Kim; Ajay B. Chitnis We have identified a novel Iroquois (Iro) gene, iro7 , in zebrafish . iro7 is expressed during gastrulation along with iro1 in a compartment of the dorsal ectoderm that includes the prospective midbrain-hindbrain...

[email protected] ) 18 9 2001 © 2001. 2001 Compartment Fgf8 Mid-hindbrain organizer Retinoic acid Wnt1 Mouse The molecular mechanisms that control development of the midbrain and cerebellum are an excellent paradigm of how stepwise inductive events can lead to patterning...

... with exogenous cadherin-6 were generated to straddle the cortico-straital boundary by electroporation at embryonic day 11.0, ectopic cadherin-6-expressing cortical cells were sorted into the striatal compartment, and the reverse was the trend for ectopic R-cadherin-expressing striatal cells. Although cadherin-6...

... of dorsoventral compartmentalization and PS integrin gene expression in the developing wing of Drosophila . Development 120 , 1805 – 1815 . 10.1242/dev.120.7.1805 Blair , S. S. ( 1993 ). Mechanisms of compartment formation: evidence that non-proliferating cells do not play a critical role...

... ). The role of apterous in the control of dorsoventral compartmentalization and PS integrin gene expression in the developing wing of Drosophila . Development 120 , 1805 – 1815 . 10.1242/dev.120.7.1805 Blair , S. S. ( 1995 ). Compartments and appendage development in Drosophila...

[email protected] ) * Present address: Beckman Institute (139-74), California Institute of Technology, Pasadena, CA, 91125, USA 05 07 1999 23 08 1999 © 1999 by Company of Biologists 1999 Cell lineage Central nervous system Clonal analysis Compartment laacZ Mouse embryo...

... of anterior cells to convert to posterior identity and establish a novel posterior compartment. This anterior/posterior conversion violates developmental lineage restrictions essential for normal growth and patterning of the disc, and thus provides an ideal model for understanding how cells change fate during...

.... Signals from dorsal and ventral ectoderm control dorso-ventral patterning while the apical ectodermal ridge (AER) controls bud outgrowth and patterning along the proximo-distal axis. We show, using cell-fate tracers, the existence of two distinct ectodermal compartments, dorsal versus ventral, in both...

... al., 1994 ) and form ventral-like tissues (Diaz-Benjumea and Cohen, 1993 ; Blair et al., 1994 ). The most widely accepted hypothesis of how selector genes control compartmentalization is that the cells throughout each compartment express, under the direct control of these genes, compartment...

... domains observed in this study and that the cellular and genetic organisation of the cerebellum are coordinated. * Author for correspondence 04 08 1997 © 1997 by Company of Biologists 1997 cell lineage cerebellum clonal analysis clonal growth compartment founder cell LaacZ...

...Artyom Kopp; Marc A. T. Muskavitch; Ian Duncan ABSTRACT We present evidence that hedgehog ( hh ) protein secreted by posterior compartment cells plays a key role in patterning the posterior portion of the anterior compartment in adult abdominal segments. Loss of function of hh in the hh ts2 mutant...

...Peter A. Lawrence; Bénédicte Sanson; Jean-Paul Vincent ABSTRACT Recent experiments on the wing disc of Drosophila have shown that cells at the interface between the anterior and posterior compartments drive pattern formation by becoming the source of a morphogen. Here we ask whether this model...

...Isabel Guillén; Jose L. Mullor; Javier Capdevila; Ernesto Sánchez-Herrero; Ginés Morata; Isabel Guerrero ABSTRACT The adult Drosophila wing (as the other appendages) is subdivided into anterior and posterior compartments that exhibit characteristic patterns. The engrailed (en) gene has been...