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Keywords: commissural axons
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Journal Articles
Journal: Development
Development (2016) 143 (12): 2183–2193.
Published: 15 June 2016
..., we identified ephrin/Eph as guidance molecules utilizing the ITAM-bearing CD3zeta (Cd247) and associated Syk kinases for the growth cone collapse response induced in vitro . Here, we show that in the developing spinal cord, Syk is phosphorylated in navigating commissural axons. By analyzing axon...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (2): 333–342.
Published: 15 January 2013
... orienting dorsal commissural (dI1) axons, BMPs supply ‘temporal’ information to commissural axons to specify their rate of growth. This information ensures that commissural axons reach subsequent signals at particular times during development. However, it remains unresolved how commissural neurons...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (19): 3837–3846.
Published: 1 October 2006
...Yan Zhu; Sarah Guthrie; Fujio Murakami Most post-crossing commissural axons turn into longitudinal paths to make synaptic connections with their targets. Mechanisms that control their rostrocaudal turning polarity are still poorly understood. We used the hindbrain as a model system to investigate...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2000) 127 (12): 2549–2561.
Published: 15 June 2000
... functional Fgf8/Ace. We find that Ace is required for the development of midline structures in the forebrain. In the absence of Ace activity, midline cells fail to adopt their normal morphology and exhibit altered patterns of gene expression. This disruption to midline tissue leads to severe commissural axon...
Journal Articles
Journal Articles
Journal Articles