... Roscovitine Colchicine Ca 2+ oscillations Cerebratulus Micrura Nemerteans In most animals, oocytes must undergo a pre-fertilization maturation process that is ultimately regulated by signaling cascades involving mitogen-activated protein kinases (MAPKs) and maturation-promoting factor(MPF...

... other), flattened (folds parted from 90° to 180°) or collapsed (folds parted more than 180°). The microtubule inhibitors colchicine and nocodazole at 10 −4 M and 6·6×10 −4 M respectively cause the cephalic neural folds of 10·4-day embryos to collapse after 60 min. At 5·2×10 −6 M the microfilament...

... on the cytoskeletal elements and the kinetic behaviour of the neural epithelium. Evidence obtained from a study of control, cytochalasin D-treated and colchicine-treated embryos, at the electron microscopic level, supports the proposed model. The longitudinally expanding cranial neural epithelium bulges between...