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Keywords: cis-acting regulator
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Journal Articles

Elimination of a long-range cis-regulatory module causes complete loss of limb-specific Shh expression and truncation of the mouse limb

Tomoko Sagai, Masaki Hosoya, Youichi Mizushina, Masaru Tamura, Toshihiko Shiroishi
Journal: Development
Development (2005) 132 (4): 797–803.
https://doi.org/10.1242/dev.01613
Published: 15 February 2005
... proposed to act as a long-range,cis-acting regulator of limb-specific Shh expression. Previous phylogenetic studies have also shown that this sequence is highly conserved among tetrapods, and even in teleost fishes. Paired fins of teleost fishes and tetrapod limbs have evolved from common ancestral...
View article titled, Elimination of a long-range cis-regulatory module causes complete loss of limb-specific Shh expression and truncation of the mouse limb
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Includes: Supplementary data