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Keywords: chimeras
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Journal Articles
Journal:
Development
Development (2013) 140 (14): 2997–3007.
Published: 15 July 2013
.... Iridophores Pigment pattern formation shady rose Chimeras Colour patterns are prominent features of many animals; they have important functions in protection against UV irradiation, camouflage, kin recognition, shoaling and sexual selection. Colour patterns in birds and mammals...
Includes: Supplementary data
Journal Articles
Patricia Ybot-Gonzalez, Dawn Savery, Dianne Gerrelli, Massimo Signore, Claire E. Mitchell, Clare H. Faux, Nicholas D. E. Greene, Andrew J. Copp
Journal:
Development
Development (2007) 134 (4): 789–799.
Published: 15 February 2007
... of a GFP expression vector into the midline neural plate, revealed defective convergent extension in both axial mesoderm and neuroepithelium, before the onset of neurulation. Chimeras containing both wild-type and Lp -mutant cells exhibited mainly wild-type cells in the midline neural plate and notochordal...
Includes: Supplementary data
Journal Articles
Martine Manuel, Petrina A. Georgala, Catherine B. Carr, Simon Chanas, Dirk A. Kleinjan, Ben Martynoga, John O. Mason, Michael Molinek, Jeni Pinson, Thomas Pratt, Jane C. Quinn, T. Ian Simpson, David A. Tyas, Veronica van Heyningen, John D. West, David J. Price
Journal:
Development
Development (2007) 134 (3): 545–555.
Published: 1 February 2007
... of late cortical progenitors specifically, and analysis of PAX77↔wild-type chimeras indicates that the defect is cell autonomous. We analyzed cortical arealization in PAX77 mice and found that, whereas the loss of Pax6 shifts caudal cortical areas rostrally, Pax6 overexpression at levels predicted...
Includes: Supplementary data
Journal Articles
Tilo Kunath, Danielle Arnaud, Gary D. Uy, Ikuhiro Okamoto, Corinne Chureau, Yojiro Yamanaka, Edith Heard, Richard L. Gardner, Philip Avner, Janet Rossant
Journal:
Development
Development (2005) 132 (7): 1649–1661.
Published: 1 April 2005
... of the epiblast or trophoblast. Chimeras generated by injection of XEN cells into blastocysts showed exclusive contribution to extra-embryonic endoderm cell types. We used female XEN cells to investigate the mechanism of X chromosome inactivation in this lineage. We observed paternally imprinted X-inactivation...
Includes: Multimedia, Supplementary data
Journal Articles
Journal:
Development
Development (2003) 130 (22): 5471–5479.
Published: 15 November 2003
...Marat Gorivodsky; Peter Lonai The epithelial b variant of Fgfr2 is active in the entire surface ectoderm of the early embryo, and later in the limb ectoderm and AER,where it is required for limb outgrowth. As limb buds do not form in the absence of Fgfr2, we used chimera analysis to investigate...
Journal Articles
Journal:
Development
Development (2001) 128 (11): 1995–2005.
Published: 1 June 2001
... which tissues require Pax3 function. We therefore used Splotch 2H mice (Sp 2H ) and lacZ -expressing Pax3 knockout mice (Sp 2G ) to generate chimeras, composed of wild-type and Pax3 −/− cells. Chimeric embryos with Pax3 −/− cells could easily be identified by PCR through the presence...
Journal Articles
Journal:
Development
Development (1999) 126 (19): 4295–4304.
Published: 1 October 1999
... that Otx2 functions both cell autonomously and non-cell autonomously in neurectoderm cells of the forebrain and midbrain to regulate expression of region-specific homeobox and cell adhesion genes. Using chimeras containing both Otx2 mutant and wild-type cells in the brain, we observe a reduction or loss...
Journal Articles
Journal:
Development
Development (1997) 124 (5): 1033–1044.
Published: 1 March 1997
..., London SE1 9RT, UK 17 12 1996 © 1997 by Company of Biologists 1997 nodal mouse gastrulation primitive endoderm chimeras Mosaic embryos developing within a nodal -deficient visceral endoderm exhibit a distinctive physical constriction between the embryonic...
Journal Articles
Journal:
Development
Development (1995) 121 (1): 19–26.
Published: 1 January 1995
...Rosemary Carpenter; Enrico S. Coen ABSTRACT Flower meristems comprise several distinct cell layers. To understand the role of cell interactions between and within these layers, we have generated plants chimeric for a key floral homeotic gene, floricaula ( flo ). These chimeras arose in Antirrhinum...
Journal Articles
Journal:
Development
Development (1992) 116 (1): 95–102.
Published: 1 September 1992
...Eva-Maria Jägerbauer; Audrey Fraser; Eberhard W. Herbst; Rashmi Kothary; Reinald Fundele ABSTRACT The ability of parthenogenetic (pg) cells to contribute to proliferating stem cell populations of postnatal aggregation chimeras was investigated. Using DNA in situ analysis, pg participation...
Journal Articles
Reinald Fundele, Sarah K. Howlett, Rashmi Kothary, Michael L. Norris, Walter E. Mills, M. Azim Surani
Journal:
Development
Development (1991) 113 (3): 941–946.
Published: 1 November 1991
...Reinald Fundele; Sarah K. Howlett; Rashmi Kothary; Michael L. Norris; Walter E. Mills; M. Azim Surani ABSTRACT The developmental potential of parthenogenetic cells derived from different mouse strains was investigated by examining their distribution in various tissues of adult aggregation chimeras...
Journal Articles
Journal:
Development
Development (1991) 113 (2): 679–687.
Published: 1 October 1991
... to the embryo. However, a contribution of AG cells in excess of 50 % was invariably lethal as development progressed to el5. A limited number of chimeras were capable of full-term development provided there was a relatively low contribution from AG cells. The distribution of AG cells in chimeras was not uniform...
Journal Articles
Journal:
Development
Development (1991) 111 (4): 969–981.
Published: 1 April 1991
... derived from all three germ layers. Furthermore, analysis of midgestation conceptuses (10.S p . c . ) and adult chimeras generated by injecting mutant ES cells into host blastocysts, provides strong evidence that the mutant cells can contribute to all extraembryonic tissues and somatic tissues, as well...
Journal Articles
András Nagy, Elen Gócza, Elizabeth Merentes Diaz, Valerie R. Prideaux, Eszter Iványi, Merja Markula, Janet Rossant
Journal:
Development
Development (1990) 110 (3): 815–821.
Published: 1 November 1990
... compromised tetraploid embryos. ES cells were capable of colonizing somatic tissues in diploid aggregation chimeras but less efficiently than ICMs of the same genotype. When ICM"-"tetraploid and IS-tetraploid chimeras were made, the newborns were almost all completely ICM-or ES-derived. as judged by GPI...
Journal Articles
Journal:
Development
Development (1990) 110 (3): 949–954.
Published: 1 November 1990
...Nigel A. Brown; Afshan Mccarthy; Lewis Wolpert Mutant iv/iv mice develop as if they have no sense of left and right, so the development of asymmetry is random: half normal, half as a mirror-image of normal, situs inversus . We have made aggregation chimeras of 8-cell stage iv/iv and +/+ embryos...
Journal Articles
Journal:
Development
Development (1990) 109 (4): 821–832.
Published: 1 August 1990
... reprint requests should be addressed. 27 04 1990 © 1990 by Company of Biologists 1990 Drosophila neurogenesis cell communication chimeras The relative importance of cell lineage and cell communication as strategies for cell determination differs among organisms and cell...
Journal Articles
Journal:
Development
Development (1990) 109 (3): 635–646.
Published: 1 July 1990
...Robin Lovell-Badge; Elizabeth Robertson ABSTRACT Chimeric mice constructed with XY embryonic stem (ES) cells that had been multiply infected with a retro viral vector were used in a genetic screen to look for mutations affecting the sex determination pathway in mice. From a small number of chimeras...
Journal Articles
Journal:
Development
Development (1989) 106 (3): 427–439.
Published: 1 July 1989
.... Quail epiblast plugs of constant size were grafted either just rostral to Hensen’s node or paranodally and the resulting chimeras were examined at selected times postgrafting. By comparing the size of the original plug, the number of cells it contained and the distribution of cells within it to those...
Journal Articles
Journal:
Development
Development (1989) 106 (1): 29–35.
Published: 1 May 1989
...Reinald Fundele; Michael L. Norris; Sheila C. Barton; Wolf Reik; M. Azim Surani The developmental potential of primitive ectoderm cells lacking paternal chromosomes was investigated by examining the distribution of parthenogenetic cells in chimeras. Using GPI-1 allozymes as marker, parthenogenetic...
Journal Articles
Journal:
Development
Development (1988) 104 (1): 175–182.
Published: 1 September 1988
... with normal embryos to produce chimeras and examined the distribution of the parthenogenetically derived cells during preimplantation and early postimplantation development. The parthenogenetic embryos were derived from a transgenic mouse line bearing a large insert, which allowed these cells to be identified...