... signaling along an unrecognized pancreatic developmental axis constitutes a chemoattractant system essential for generating the hallmark morphogenetic properties of pancreatic islets. Unexpectedly, Sema3a- and Nrp2-mediated control of islet morphogenesis is strikingly homologous to mechanisms that regulate...

... towards a localized Fgf source in a chemoattractive fashion during fin initiation. We have previously shown that suboptimal doses of Tbx5a morpholino can reduce the size of larval pectoral fins and cause tissue gaps preferentially on the anterior side of the endoskeletal disc ( Ahn et al., 2002...

... into the proximal cardiac outflow tract. 31 5 2001 ©2001. 2001 Semaphorin 3C Mouse Cardiac neural crest Interrupted aortic arch Persistent truncus arteriosus PlexinA2 Chemoattractant Sema3C Classic studies performed almost 20 years ago demonstrated that perturbations of migrating...

... in the lateral GE and the sulcus between the lateral and medial ridges of the GE (ISS), as well as evidence implicating the axonal chemoattractant netrin-1 in mediating these effects. Explants of lateral GE and ISS obtained from E12.5 and E13.5 mouse forebrain have a strong effect on both the outgrowth...