... Cerebral cortex International FOXG1 Research Foundation Scuola Internazionale Superiore di Studi Avanzati http://dx.doi.org/10.13039/100013104 SISSA: Scuola Internazionale Superiore di Studi Avanzati Foxg1 encodes an evolutionarily ancient transcription factor...

... of Biologists Ltd 2021 Summary: The double-stranded RNA-binding protein STAU2 associates dynamically with RNA determinants that contribute to intermediate progenitor cell diversity and cortical lamination during mouse cerebral cortex development. RNA-binding protein STAU2 RIP-seq Cerebral...

...Matthieu X. Moreau; Yoann Saillour; Andrzej W. Cwetsch; Alessandra Pierani; Frédéric Causeret ABSTRACT In the developing cerebral cortex, how progenitors that seemingly display limited diversity end up producing a vast array of neurons remains a puzzling question. The prevailing model suggests...

...Sonia Najas; Isabel Pijuan; Anna Esteve-Codina; Susana Usieto; Juan D. Martinez; An Zwijsen; Maria L. Arbonés; Elisa Martí; Gwenvael Le Dréau ABSTRACT The growth and evolutionary expansion of the cerebral cortex are defined by the spatial-temporal production of neurons, which itself depends...

... in the developing cerebral cortex. * Present address: Department of Molecular, Cell and Systems Biology, University of California, Riverside, CA 92521, USA. ‡ Authors for correspondence ( [email protected] ; [email protected] ) Competing interests The authors declare no competing or financial...

... neuronal connections via selective axon guidance. The EMX transcription factors are essential for early patterning of the cerebral cortex, but whether EMX1 mediates interhemispheric connectivity by controlling corpus callosum formation remains unclear. Here, we demonstrate that in mice on the C57Bl/6...

... experimental manipulation in embryos is difficult, such as non-human primates ( Wunderlich et al., 2014 ). This might shed further light on the evolutionary conservation and divergence of various other aspects of brain development, such as the gyration patterns of the cerebral cortex that have been...

...Peter Kirwan; Benita Turner-Bridger; Manuel Peter; Ayiba Momoh; Devika Arambepola; Hugh P. C. Robinson; Frederick J. Livesey A key aspect of nervous system development, including that of the cerebral cortex, is the formation of higher-order neural networks. Developing neural networks undergo...

... using the mouse embryonic cerebral cortex as an experimental model. We combined atomic force microscopy measurements of tissue and cellular stiffness with immunostaining of specific markers of neural differentiation to correlate the value of stiffness with the characteristic features of tissues...

... zone) at the pallial-subpallial boundary (grey arrowhead) at P15. (G) CLoNe at the hypothalamus (HT) revealed many late-born astrocytes and multifluorescence at the progenitors (arrowheads) aligning the third ventricle (IIIv) at P15. A, amygdala; CC, cerebral cortex; wm, white matter; St, striatum...

... ) Competing interests statement The authors declare no competing financial interests. © 2013. Published by The Company of Biologists Ltd 2013 Adult neurogenesis Cerebral cortex Neuronal specification Olfactory bulb Subventricular zone In the developing telencephalon...

... Neuronal migration Neuronal identity Axon pathfinding Pyramidal neuron Neuronal circuits Cerebral cortex The cerebral cortex, an extensive sheet of neural tissue at the most superficial part of the cerebral hemispheres, is involved in a variety of higher cognitive, emotional...

... - 1933 . Alcamo E. A. , Chirivella L. , Dautzenberg M. , Dobreva G. , Farinas I. , Grosschedl R. , McConnell S. K. ( 2008 ). Satb2 regulates callosal projection neuron identity in the developing cerebral cortex . Neuron 57 , 364 - 377 . Armentano M...

... in the mammalian cerebral cortex . Development 132 , 1295 - 1304 . Molyneaux B. J. , Arlotta P. , Menezes J. R. , Macklis J. D. ( 2007 ). Neuronal subtype specification in the cerebral cortex . Nat. Rev. Neurosci. 8 , 427 - 437 . Ohtsuka T. , Ishibashi M...

...Jeremy N. Pulvers; Wieland B. Huttner The extent of apoptosis of neural progenitors is known to influence the size of the cerebral cortex. Mouse embryos lacking Brca1 , the ortholog of the human breast cancer susceptibility gene BRCA1 , show apoptosis in the neural tube, but the consequences...

... through Gdf11 in the cerebral cortex( Fig. 9 ), a potential role for other TGFβ family ligands cannot be ruled out. Alternatively, it may be that, in some neural structures, the positive regulation of pro-neurogenic signals, such as FGFs, is of greater importance than the negative regulation of anti...

...Anne K. Voss; Joanne M. Britto; Mathew P. Dixon; Bilal N. Sheikh; Caitlin Collin; Seong-Seng Tan; Tim Thomas Neuronal migration is integral to the development of the cerebral cortex and higher brain function. Cortical neuron migration defects lead to mental disorders such as lissencephaly...

.... and Rubenstein, J. L. ( 1997 ). Interneuron migration from basal forebrain to neocortex: dependence on Dlx genes. Science 278 , 474 -476. Angevine, J. B. and Sidman, R. L. ( 1961 ). Autoradiographic study of cell migration during histogenesis of cerebral cortex in the mouse. Nature 192 , 766 -768...

...Toshio Ohshima; Motoyuki Hirasawa; Hidenori Tabata; Tetsuji Mutoh; Tomoko Adachi; Hiromi Suzuki; Keiko Saruta; Takuji Iwasato; Shigeyoshi Itohara; Mistuhiro Hashimoto; Kazunori Nakajima; Masaharu Ogawa; Ashok B. Kulkarni; Katsuhiko Mikoshiba The mammalian cerebral cortex consists of six layers...

... in expression of cortical lamination markers. The alterations in cortical cytoarchitecture result in behavioral abnormalities suggestive of a deficient processing of visual and spatial memory cues in the cerebral cortex of adult Zbtb20 transgenic mice. Overall,our in vivo data suggest that Zbtb20 functions...