...Lucretia Kwenda; Caitriona M. Collins; Anna A. Dattoli; Elaine M. Dunleavy The centromere-specific histone CENP-A is the key epigenetic determinant of centromere identity. Whereas most histones are removed from mature sperm, CENP-A is retained to mark paternal centromeres. In Drosophila males we...

... to pericentric heterochromatin during the transition to the first mitosis. This stage is also characterized by a striking kinetochore size asymmetry established by differences in CENP-C protein between the parental genomes. Loss of ATRX results in increased centromeric mitotic recombination, a high frequency...

... no competing financial interests 12 11 2013 24 2 2014 © 2014. Published by The Company of Biologists Ltd 2014 Nucleolus precursor body Centromere Chromosome bridging Satellite DNA Replication stress Mice The transition from meiosis to mitosis is a crucial period in animal...

... chromosomes segregate randomly, the dyad univalents formed an ordered metaphase plate and underwent an equational division. This suggests a requirement for DYAD for chromosome synapsis and centromere configuration in female meiosis. The dyad mutant showed increased and persistent expression of a meiosis...

...Chris Tyler-Smith ABSTRACT Alphoid satellite DNA is a family of sequences with an approximately 170 bp periodicity which is found near the centromere of all human chromosomes. The structure of the human Y-chromosome alphoid DNA has been studied in two somatic cell hybrids, 3E7 and 853 ( Tyler-Smith...