... a functional Tubulin-binding co-factor Cd1 (TBCCd1) protein, indicating that TBCCd1 and PP2A are two essential components of the cellular machinery that regulates the first cell division and mediates basal cell fate determination. * These authors contributed equally to this work ‡ Authors...

... and invertebrates. * Author for correspondence ( [email protected] ) Competing interests statement The authors declare no competing financial interests. © 2012. Published by The Company of Biologists Ltd 2012 ADAM Notch Ectodomain shedding Cell fate determination Differentiation...

... identity. This bi-potency is lost in mature DG cells, although Prox1 is still required for correct gene expression in DG granule cells. Thus, our data indicate that Prox1 acts as a postmitotic cell fate determinant for DG granule cells over the CA3 pyramidal cell fate and is crucial for maintenance...

... expression of thyroid hormone receptor 2 and cone opsins in the developing mouse retina . J. Neurosci. 28 , 749 - 756 . Livesey F. J. , Cepko C. L. ( 2001 ). Vertebrate neural cell-fate determination: lessons from the retina . Nat. Rev. Neurosci. 2 , 109 - 118 . Livne-Bar I...

...Lily L. Wong; David H. Rapaport Extrinsic cues and intrinsic competence act in concert for cell fate determination in the developing vertebrate retina. However, what controls competence and how precise is the control are largely unknown. We studied the regulation of competence by examining...

.... W., Wan, H. and Whitsett, J. A. ( 2002 ). GATA-6 and thyroid transcription factor-1 directly interact and regulate surfactant protein-C gene expression. J. Biol. Chem. 277 , 4519 -4525. Livesey, F. J. and Cepko, C. L. ( 2001 ). Vertebrate neural cell-fate determination: lessons from...

...Torsten Bossing; Andrea H. Brand The Drosophila ventral midline has proven to be a useful model for understanding the function of central organizers during neurogenesis. The midline is similar to the vertebrate floor plate, in that it plays an essential role in cell fate determination...

... 28 9 2004 © 2004. 2004 Pre-placodal ectoderm Neural crest foxD3 zic2 sox2 sox3 keratin dlx5 dlx6 Cell fate determination Patterning Xenopus It was discovered over a century ago that the cranial sensory organs of vertebrates arise from discrete areas...

... Cerebral cortex Cortical plate Neuroepithelium Subventricular zone Asymmetric cell division Cell migration Cell cycle Cell fate determination Layer formation Neurogenin2 Slice culture Mouse Asymmetric cell division events are important for the generation of cellular diversity...

... epithelium to signal properly to the retina. * Author for correspondence (e-mail: [email protected] ) 17 10 2000 27 11 2000 © 2001 by Company of Biologists 2001 Cell fate determination Danio rerio Eye Mutation Polarity Proliferation RPE Two major...

...J. Lisa Zheng; Jianyong Shou; Francois Guillemot; Ryoichiro Kageyama; Wei-Qiang Gao ABSTRACT Hair cell fate determination in the inner ear has been shown to be controlled by specific genes. Recent loss-of-function and gain-of-function experiments have demonstrated that Math1 , a mouse homolog...

... in the PS1 −/− brain, we examined the expression of genes in the Notch signalling pathway, which is known to be involved in cell-fate determination during neurogenesis in Drosophila ( Artavanis-Tsakonas et al., 1999 ). The role of Notch receptors in murine neurogenesis is poorly understood. Mice...

... Institute of Genetics, Mishima, Shizuoka 411-8540, Japan ¶ Author for correspondence (e-mail: [email protected] ) 6 April 1999 9 February 1999 © 1999 by Company of Biologists 1999 glial cells missing (gcm) Cell fate determination Neuroblast Glia Neuron...

... , F. , Taylor , A. and Brownlee , C. ( 1994 ). Cell fate determination by the cell wall in early Fucus development . Science 263 , 1421 – 1423 . 10.1126/science.263.5152.1421 Berger , F. and Brownlee , C. ( 1995 ). Physiology and development of protoplasts...

... of Biologists 1997 Drosophila sense organ neuronal identity cell fate determination The sensory neurons of arthropods belong to either of two main types, called type I and type II ( Zacharuk, 1985 ). Type I neurons are characterized by their single dendrite whose distal part is a modified...

... © 1995 by Company of Biologists 1995 XlPOU 2 neural induction POU noggin Xenopus blastomere cell fate determination The mechanisms for determining what prompts a cell to select an epidermal versus neuronal pathway are not well understood, but the process probably involves...

.../gad.6.12b.2443 05 02 1994 © 1994 by Company of Biologists 1994 Drosophila oogenesis cell fate determination RNA localization cytoskeleton Cytoplasmic localization of determinative molecules can create the molecular asymmetries required for the establishment...

...Fred Tata; David A. Hartley ABSTRACT Molecular and genetic data predict that the Enhancer of split locus functions at the end of a pathway dictating appropriate cell fate determination in a number of developmental contexts. We have sought to dissect the role individual member genes of the complex...

... development by default. Recent independent experiments by Altshuler and Cepko (1992) , however, suggest that the diffusible rodpromoting signal(s) produced by neonatal retinal cells influences cell fate determination rather than cell survival or just terminal differentiation. In their experiments...

... development cell fate determination conditional allele phototaxis © 1989 by Company of Biologists 1989 13 09 1989 ...