... in an integrated mechanochemical signaling system to ultimately control cardiomyocyte proliferation in the newborn mouse heart. Rho-associated kinase Nonmuscle myosin Heart Cardiomyocyte Cell adhesion Cadherin Integrin Adherens junctions Focal adhesions Fibronectin Yap Mouse National...

... epithelial migration driven by pulsatile actomyosin contractility. Palate Collective cell migration Apoptosis Cell extrusion Tgfβ Cleft palate Cleft lip Craniofacial Live imaging Fusion Actomyosin Cell adhesion Non-muscle myosin II NMIIA Mouse National Institute of Dental...

.... A. and Costell , M. ( 2017 ). The fibronectin synergy site re-enforces cell adhesion and mediates a crosstalk between integrin classes . Elife 6 , e22264 . 10.7554/eLife.22264 Bennett , M. , Cantini , M. , Reboud , J. , Cooper , J. M. , Roca-Cusachs , P. and Salmeron...

... provided that the original work is properly attributed. Highlighted Article: Tissue-resident macrophages are indispensable mediators of lymphatic vessel formation during heart development, and function to remodel the vascular plexus. Macrophages Hyaluronan Cell adhesion Cardiac...

... migration – are reviewed, with a focus on Drosophila , a powerful model for studying these events. Cell adhesion Cytoskeleton Drosophila Morphogenesis During morphogenesis, the body is assembled and remodeled by cell shape changes and movements ( Gillard and Röper, 2020 ). These events...

... restriction process remain unclear. Here, using novel fluorescent knock-in reporters, live imaging, Cre/lox-mediated lineage tracing, atomic force microscopy-based cell adhesion assays and mutant analysis, we analyze the process of lineage restriction at the MHB and provide mechanistic details. Specifically...

.... Cadherins, the major cell adhesion molecules, form adherens junctions connecting epithelial cells. Numerous studies of Bilateria have shown that cadherins are associated with the regulation of cell differentiation, cell shape changes, cell migration and tissue morphogenesis. To date, the role of cadherins...

...Alexia Vite; Caimei Zhang; Roslyn Yi; Sabrina Emms; Glenn L. Radice ABSTRACT Shortly after birth, muscle cells of the mammalian heart lose their ability to divide. At the same time, the N-cadherin/catenin cell adhesion complex accumulates at the cell termini, creating a specialized type of cell...

... cue for setting up the apical-basal polarity axis, is regulated by active Rap1 acting both through, and independently of, the Cno Rap1-binding domain. Cadherin Cell adhesion Morphogenesis Epithelia Polarity Canoe/Afadin, Drosophila Cell polarity – the ability to differentially...

...William P. Daley; Kazue Matsumoto; Andrew D. Doyle; Shaohe Wang; Brian J. DuChez; Kenn Holmbeck; Kenneth M. Yamada Branching morphogenesis of developing organs requires coordinated but poorly understood changes in epithelial cell-cell adhesion and cell motility. We report that Btbd7 is a crucial...

...Loïc Sauteur; Markus Affolter; Heinz-Georg Belting The cardiovascular system forms during early embryogenesis and adapts to embryonic growth by sprouting angiogenesis and vascular remodeling. These processes require fine-tuning of cell-cell adhesion to maintain and re-establish endothelial contacts...

..., with structure emerging after the clustering of ureteric epithelial cells, a process consistent with models of random cell movement with preferential cell adhesion. Ureteric epithelialisation rapidly followed the formation of ureteric cell clusters with the reformation of nephron-forming niches representing...

.... and Bosma , M. M. ( 2009 ). Properties and mechanisms of spontaneous activity in the embryonic chick hindbrain . Dev. Neurobiol.   69 , 477 - 490 . 10.1002/dneu.20712 Kintner , C. ( 1992 ). Regulation of embryonic cell adhesion by the cadherin cytoplasmic domain . Cell   69 , 225...

... in the developing chick embryo by promoting CDH2 (N-cadherin) endocytosis. Somitogenesis Tissue morphogenesis Cell adhesion Cadherin Protocadherin Paraxial mesoderm Boundary formation Endocytosis Somitogenesis is an early developmental process whereby pairs of epithelial spheres, called somites...

... that the apoptotic cell is expelled. In parallel, contraction of actomyosin cables formed in apoptotic and neighboring cells drives cell extrusion. To date, the coordination between the dynamics of cell adhesion and the progressive changes in tissue tension around an apoptotic cell is not fully understood. Live...

...Stéphane Verger; Salem Chabout; Emilie Gineau; Grégory Mouille Cell-to-cell adhesion in plants is mediated by the cell wall and the presence of a pectin-rich middle lamella. However, we know very little about how the plant actually controls and maintains cell adhesion during growth and development...

... basis of inductive tissue interactions and for studying cataract, the leading cause of blindness. The formation of tightly controlled cell-cell adhesions and cell-matrix junctions between lens epithelial (LE) cells, between lens fiber (LF) cells, and between these two cell populations enables...

..., we analyse cell adhesion in Xenopus embryonic tissues and determine a number of parameters, including tissue surface tension (as a measure of cohesion), cell contact fluctuation and cortical tension. In the tissues studied, the ratio of surface tension to viscosity, which has the dimension...

...Matthew R. Clay; Mary C. Halloran The epithelial-to-mesenchymal transition (EMT) is a complex change in cell phenotype that is important for cell migration, morphogenesis and carcinoma metastasis. Loss of epithelial cell adhesion and tight regulation of cadherin adhesion proteins are crucial...

... approach, we investigate changes in cell-cell adhesion underlying this transition by monitoring cadherin receptor localisation and stability. This reveals that while cadherin 2 is expressed across the entire tissue, functional apical junctions are first assembled in the transition zone and become...