... . 10.1016/j.semcdb.2017.11.010 Hollnagel , A. , Grund , C. , Franke , W. W. and Arnold , H.-H. ( 2002 ). The cell adhesion molecule M-cadherin is not essential for muscle development and regeneration . Mol. Cell. Biol. 22 , 4760 - 4770 . 10.1128/MCB.22.13.4760-4770.2002...

... . 10.1083/jcb.201309092 Bertocchi , C. , Wang , Y. , Ravasio , A. , Hara , Y. , Wu , Y. , Sailov , T. , Baird , M. A. , Davidson , M. W. , Zaidel-Bar , R. , Toyama , Y. et al. ( 2017 ). Nanoscale architecture of cadherin-based cell adhesions . Nat. Cell...

... epithelial migration driven by pulsatile actomyosin contractility. Palate Collective cell migration Apoptosis Cell extrusion Tgfβ Cleft palate Cleft lip Craniofacial Live imaging Fusion Actomyosin Cell adhesion Non-muscle myosin II NMIIA Mouse National Institute of Dental...

...: This Review summarizes the formation and function of focal adhesions, highlighting similarities and differences in how these macromolecular assemblies are used in in vitro and in vivo contexts. Cell adhesion Cell migration Focal adhesion Integrin National Institutes of Health http...

... of VEGFC, a potent lymphangiogenic factor known to be expressed by cardiac macrophages in a myocardial infarction setting ( Vieira et al., 2018 ), and cell-adhesion molecules previously implicated in leukocyte-endothelium interactions during immune response, specifically integrin subunit β2 (ITGB2; also...

... migration – are reviewed, with a focus on Drosophila , a powerful model for studying these events. Cell adhesion Cytoskeleton Drosophila Morphogenesis During morphogenesis, the body is assembled and remodeled by cell shape changes and movements ( Gillard and Röper, 2020 ). These events...

... restriction process remain unclear. Here, using novel fluorescent knock-in reporters, live imaging, Cre/lox-mediated lineage tracing, atomic force microscopy-based cell adhesion assays and mutant analysis, we analyze the process of lineage restriction at the MHB and provide mechanistic details. Specifically...

.... Cadherins, the major cell adhesion molecules, form adherens junctions connecting epithelial cells. Numerous studies of Bilateria have shown that cadherins are associated with the regulation of cell differentiation, cell shape changes, cell migration and tissue morphogenesis. To date, the role of cadherins...

...Alexia Vite; Caimei Zhang; Roslyn Yi; Sabrina Emms; Glenn L. Radice ABSTRACT Shortly after birth, muscle cells of the mammalian heart lose their ability to divide. At the same time, the N-cadherin/catenin cell adhesion complex accumulates at the cell termini, creating a specialized type of cell...

... Gumbiner , B. , Stevenson , B. and Grimaldi , A. ( 1988 ). The role of the cell adhesion molecule uvomorulin in the formation and maintenance of the epithelial junctional complex . J. Cell Biol.   107 , 1575 - 1587 . 10.1083/jcb.107.4.1575 Harris , T. J. C. ( 2012 ). Adherens...

...William P. Daley; Kazue Matsumoto; Andrew D. Doyle; Shaohe Wang; Brian J. DuChez; Kenn Holmbeck; Kenneth M. Yamada Branching morphogenesis of developing organs requires coordinated but poorly understood changes in epithelial cell-cell adhesion and cell motility. We report that Btbd7 is a crucial...

...Loïc Sauteur; Markus Affolter; Heinz-Georg Belting The cardiovascular system forms during early embryogenesis and adapts to embryonic growth by sprouting angiogenesis and vascular remodeling. These processes require fine-tuning of cell-cell adhesion to maintain and re-establish endothelial contacts...

..., with structure emerging after the clustering of ureteric epithelial cells, a process consistent with models of random cell movement with preferential cell adhesion. Ureteric epithelialisation rapidly followed the formation of ureteric cell clusters with the reformation of nephron-forming niches representing...

..., the question of how nuclei form is unresolved. Here, we demonstrate that cell adhesion and spontaneous activity (SA), in the form of observable calcium transients, converge to shape motor nuclei of the vertebrate brainstem ( Fig. 1 A). During nucleogenesis, facial and abducens motor neurons originate from...

... . J. Cell Biol.   174 , 301 - 313 . 10.1083/jcb.200602062 Chen , X. , Koh , E. , Yoder , M. and Gumbiner , B. M. ( 2009 ). A protocadherin-cadherin-FLRT3 complex controls cell adhesion and morphogenesis . PLoS ONE   4 , e8411 . 10.1371/journal.pone.0008411 Dale...

... that the apoptotic cell is expelled. In parallel, contraction of actomyosin cables formed in apoptotic and neighboring cells drives cell extrusion. To date, the coordination between the dynamics of cell adhesion and the progressive changes in tissue tension around an apoptotic cell is not fully understood. Live...

...Stéphane Verger; Salem Chabout; Emilie Gineau; Grégory Mouille Cell-to-cell adhesion in plants is mediated by the cell wall and the presence of a pectin-rich middle lamella. However, we know very little about how the plant actually controls and maintains cell adhesion during growth and development...

... basis of inductive tissue interactions and for studying cataract, the leading cause of blindness. The formation of tightly controlled cell-cell adhesions and cell-matrix junctions between lens epithelial (LE) cells, between lens fiber (LF) cells, and between these two cell populations enables...

..., we analyse cell adhesion in Xenopus embryonic tissues and determine a number of parameters, including tissue surface tension (as a measure of cohesion), cell contact fluctuation and cortical tension. In the tissues studied, the ratio of surface tension to viscosity, which has the dimension...

...Matthew R. Clay; Mary C. Halloran The epithelial-to-mesenchymal transition (EMT) is a complex change in cell phenotype that is important for cell migration, morphogenesis and carcinoma metastasis. Loss of epithelial cell adhesion and tight regulation of cadherin adhesion proteins are crucial...