... effects and that tek is missing in most fish. Tek ( Tie2 ) Cardiovascular development Genome editing Morpholino Evolutionary genetics Functional diversification The cardiovascular system is one of the first organs to form and function, and its development is regulated by complex...

... by the NC, leading to activation of Notch and differentiation of VSMCs. Our data demonstrate an essential role of the localized synthesis of Fn1 in cardiovascular development and spatial regulation of Notch signaling. * Author for correspondence ( [email protected] ) Competing interests...

... . Differentiation   33 , 239 - 246 . 10.1111/j.1432-0436.1987.tb01563.x High , F. A. , Zhang , M. , Proweller , A. , Tu , L. , Parmacek , M. S. , Pear , W. S. and Epstein , J. A. ( 2007 ). An essential role for Notch in neural crest during cardiovascular development...

... to this work Competing interests statement The authors declare no competing financial interests. 21 1 2013 © 2013. Published by The Company of Biologists Ltd 2013 UBIAD1 Vitamin K2 Cardiovascular development Zebrafish Endothelial cells As vertebrates undergo...

... stimuli and signaling pathways. * Author for correspondence ( [email protected] ) © 2012. Valvulogenesis Hematopoiesis Angiogenesis Cilia Left-right organizer Stokes flow Navier–Stokes equations Cardiovascular development Mechanodetection Fluids (see Glossary...

.... 2008 Cardiovascular development Cox2 (Ptgs2) Microscopy Prostaglandins SPIM Zebrafish The heart is the earliest functioning organ and is required soon after gastrulation, early in its own morphogenesis. Its function must change as its morphology changes: it first acts as a simple...

...-mail: [email protected] ) 4 9 2003 © The Company of Biologists Limited 2003 2003 Cardiovascular development Pharyngeal arch FGF8 Endoderm Heart field Pharyngeal arch artery Congenital heart disease Vasculogenesis Aortic arch Outflow tract Coronary artery Thymus Parathyroid...

... development Cardiovascular development The body plan organisation and morphogenesis of the organs result from the sequential activation and spatio-temporal combinatorial expression of various genes, including transcription factors, growth factors and their associated receptors. Each member...

.... These data suggest that changes in the cyto-plasmic domain of PECAM-1 may affect its function during cardiovascular development, and are consistent with our earlier report that systematic truncation of the cytoplasmic domain of human PECAM-1 resulted in changes in its ligand specificity, divalent cation...