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Keywords: cGMP
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Journal Articles
Journal: Development
Development (2014) 141 (1): 136–147.
Published: 01 January 2014
...Kayam Chak; Alex L. Kolodkin The second messengers cAMP and cGMP modulate attraction and repulsion mediated by neuronal guidance cues. We find that the Drosophila receptor guanylyl cyclase Gyc76C genetically interacts with Semaphorin 1a ( S e ma-1a ) and physically associates with the Sema-1a...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (11): 1869–1878.
Published: 01 June 2009
... signal from the somatic cells is cGMP. Using FRET-based cyclic nucleotide sensors in follicle-enclosed mouse oocytes, we find that cGMP passes through gap junctions into the oocyte,where it inhibits the hydrolysis of cAMP by the phosphodiesterase PDE3A. This inhibition maintains a high concentration...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (11): 2707–2714.
Published: 01 June 2004
... and affected by drugs interfering in the cGMP signaling pathway. The sensitivity threshold of the response was significantly augmented by sildenafil citrate (SC), an inhibitor of cGMP-specific phosphodiesterases in animals. NO distribution inside pollen tubes was investigated using DAF2-DA and was shown...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2003) 130 (17): 3977–3987.
Published: 01 September 2003
...Annely Haase; Gerd Bicker The dynamic regulation of nitric oxide synthase (NOS) activity and cGMP levels suggests a functional role in the development of nervous systems. We report evidence for a key role of the NO/cGMP signalling cascade on migration of postmitotic neurons in the enteric nervous...
Journal Articles
Journal: Development
Development (2001) 128 (22): 4405–4414.
Published: 15 November 2001
...+ is derived from intracellular stores, but the principal signaling and release system involved has not yet been agreed upon. Possible candidates are the inositol 1,4,5-trisphosphate receptor/channel (IP 3 R) and the ryanodine receptor/channel (RyR) which is activated by cGMP or cyclic ADP-ribose (cADPR). Thus...