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Keywords: cAMP-dependent protein kinase
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Journal Articles

The hedgehog-PKA pathway regulates two distinct steps of the differentiation of retinal ganglion cells: the cell-cycle exit of retinoblasts and their neuronal maturation

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Ichiro Masai, Masahiro Yamaguchi, Noriko Tonou-Fujimori, Atsuko Komori, Hitoshi Okamoto
Journal: Development
Development (2005) 132 (7): 1539–1553.
https://doi.org/10.1242/dev.01714
Published: 1 April 2005
... the progression of the differentiation of retinal ganglion cells (RGCs) in zebrafish. However, the progression of neurogenesis seems to be only mildly delayed by genetic or chemical blockade of the Hh signalling pathway. Here, we show that cAMP-dependent protein kinase (PKA) effectively inhibits the progression...
View articletitled, The hedgehog-PKA pathway regulates two distinct steps of the differentiation of retinal ganglion cells: the cell-cycle exit of retinoblasts and their neuronal maturation
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Journal Articles

YakA, a protein kinase required for the transition from growth to development in Dictyostelium

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Glaucia Mendes Souza, Sijieand Lu, Adam Kuspa
Journal: Development
Development (1998) 125 (12): 2291–2302.
https://doi.org/10.1242/dev.125.12.2291
Published: 15 June 1998
... York, NY . Garrett , S. and Broach , J. (1989). Loss of Ras activity in Saccharomyces cerevisiae is suppressed by disruptions of a new kinase gene, YAKI , whose product may act downstream of the cAMP-dependent protein kinase . Genes Dev . 3 , 1336 – 1348 . 10.1101/gad.3.9.1336...
View articletitled, YakA, a protein kinase required for the transition from growth to development in Dictyostelium
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Journal Articles

cAMP-dependent protein kinase differentially regulates prestalk and prespore differentiation during Dictyostelium development

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Sandra K. O. Mann, Richard A. Firtel
Journal: Development
Development (1993) 119 (1): 135–146.
https://doi.org/10.1242/dev.119.1.135
Published: 1 September 1993
...Sandra K. O. Mann; Richard A. Firtel ABSTRACT We and others have previously shown that cAMP-dependent protein kinase (PKA) activity is essential for aggregation, induction of prespore gene expression and multicellular development in Dictyostelium . In this manuscript, we further examine...
View articletitled, cAMP-dependent protein kinase differentially regulates prestalk and prespore differentiation during Dictyostelium development
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Journal Articles

A repressor controls the timing and spatial localisation of stalk cell-specific gene expression in Dictyostelium

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A. J. Harwood, A. Early, J. G. Williams
Journal: Development
Development (1993) 118 (4): 1041–1048.
https://doi.org/10.1242/dev.118.4.1041
Published: 1 August 1993
... of cAMP-dependent protein kinase (PKA) in prestalk cells blocks both stalk cell maturation and ecmB gene expression. We show that the block to gene expression correlates precisely with the presence of a functional repressor element and this is consistent with the notion that expression of the ecmB gene...
View articletitled, A repressor controls the timing and spatial localisation of stalk cell-specific gene expression in Dictyostelium
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