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Keywords: cAMP signaling
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Journal Articles
Shinichiro Ogawa, James Surapisitchat, Carl Virtanen, Mina Ogawa, Maryam Niapour, Kim S. Sugamori, Shuang Wang, Laura Tamblyn, Chantal Guillemette, Ewa Hoffmann, Bin Zhao, Stephen Strom, Rebecca R. Laposa, Rachel F. Tyndale, Denis M. Grant, Gordon Keller
Journal:
Development
Development (2013) 140 (15): 3285–3296.
Published: 1 August 2013
... been challenging to date, owing to the fact that the regulatory pathways that control hepatocyte maturation are poorly understood. Here, we show that the combination of three-dimensional cell aggregation and cAMP signaling enhance the maturation of hPSC-derived hepatoblasts to a hepatocyte-like...
Includes: Supplementary data
