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1-6 of 6
Keywords: bmi1
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Journal Articles
In collection:
Stem cells & regeneration
Bradley J. Goldstein, Garrett M. Goss, Rhea Choi, Dieter Saur, Barbara Seidler, Joshua M. Hare, Nirupa Chaudhari
Journal:
Development
Development (2016) 143 (23): 4394–4404.
Published: 1 December 2016
... . Characterizing successful cultures, we identified expression of BMI1 and other Polycomb proteins not previously identified in olfactory basal cells but known to be essential for self-renewal in other stem cell populations. Inducible fate mapping demonstrates that BMI1 is expressed in vivo by multipotent OE...
Includes: Supplementary data
Journal Articles
Andrea Barabino, Vicky Plamondon, Mohamed Abdouh, Wassim Chatoo, Anthony Flamier, Roy Hanna, Shufeng Zhou, Noboru Motoyama, Marc Hébert, Joëlle Lavoie, Gilbert Bernier
Journal:
Development
Development (2016) 143 (9): 1571–1584.
Published: 1 May 2016
... cell type. Of these, rod and cone photoreceptors represent the functional unit of light detection and phototransduction and are frequently affected in retinal degenerative diseases. During mouse development, the Polycomb group protein Bmi1 is expressed in immature retinal progenitors and differentiated...
Includes: Supplementary data
Journal Articles
In collection:
Stem cells & regeneration
Erika López-Arribillaga, Verónica Rodilla, Luca Pellegrinet, Jordi Guiu, Mar Iglesias, Angel Carlos Roman, Susana Gutarra, Susana González, Pura Muñoz-Cánoves, Pedro Fernández-Salguero, Freddy Radtke, Anna Bigas, Lluís Espinosa
Journal:
Development
Development (2015) 142 (1): 41–50.
Published: 1 January 2015
...-specific genetic mouse models and analyzed the expression of intestinal differentiation markers. Importantly, we found that activation of β-catenin partially rescues the differentiation phenotype of Rbpj deletion mutants, but not the loss of the ISC compartment. Moreover, we identified Bmi1 , which...
Includes: Supplementary data
Journal Articles
Journal:
Development
Development (2006) 133 (24): 4957–4968.
Published: 15 December 2006
... complexes of diverse composition and function exhibit cooperative interaction or hierarchical interdependency at target loci. The present study interrogated the genetic, biochemical and molecular interaction of BMI1 and EED, pivotal constituents of heterologous Polycomb complexes, in the regulation...
Journal Articles
Takeshi Akasaka, Maarten van Lohuizen, Nathalie van der Lugt, Yoko Mizutani-Koseki, Masamoto Kanno, Masaru Taniguchi, Miguel Vidal, Mark Alkema, Anton Berns, Haruhiko Koseki
Journal:
Development
Development (2001) 128 (9): 1587–1597.
Published: 1 May 2001
... complexes to maintain spatially restricted expression of Hox cluster genes. Unlike in Drosophila , in mammals Polycomb group (PcG) genes are represented as highly related gene pairs, indicative of duplication during metazoan evolution. Mel18 and Bmi1 are mammalian homologs of Drosophila Posterior sex combs...
Journal Articles
Sophie Bel, Nathalie Coré, Malek Djabali, Karin Kieboom, Nathalie Van der Lugt, Mark J. Alkema, Maarten Van Lohuizen
Journal:
Development
Development (1998) 125 (18): 3543–3551.
Published: 15 September 1998
... phenotypes of compound mutants for two Polycomb group genes bmi1 and M33 . We show that mice deficient for both bmi1 and M33 present stronger homeotic transformations of the axial skeleton as compared to each single Polycomb group mutant, indicating strong dosage interactions between those two genes...