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1-8 of 8
Keywords: bapx1
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Journal Articles
Journal:
Development
Development (2010) 137 (17): 2927–2937.
Published: 1 September 2010
.... Note that 5-HT2B misexpression did not alter XHoxa2 expression in the second branchial arch. Since Hoxa2 is able to restrict Xbap/bapx1 expression in the first branchial arch by repressing its transcription in the second branchial arch (Pasqualetti et al., 2000 ; Miller et al., 2004 ; Balzinger et...
Includes: Supplementary data
Journal Articles
Sylvain Provot, Hervé Kempf, L. Charles Murtaugh, Ung-il Chung, Dae-Won Kim, Jay Chyung, Henry M. Kronenberg, Andrew B. Lassar
Journal:
Development
Development (2006) 133 (4): 651–662.
Published: 15 February 2006
..., expression of Nkx3.2/Bapx1 in the growth plate is restricted to the proliferative zone and is downregulated as chondrocyte maturation begins. Nkx3.2/Bapx1 expression is lost in the growth plates of mice engineered to lack PTHrP signaling and, conversely, is maintained by ectopic expression of PTHrP...
Journal Articles
The splanchnic mesodermal plate directs spleen and pancreatic laterality,and is regulated by Bapx1/Nkx3.2
Available to PurchaseJacob Hecksher-Sørensen, Robert P. Watson, Laura A. Lettice, Palle Serup, Lorraine Eley, Carlo De Angelis, Ulf Ahlgren, Robert E. Hill
Journal:
Development
Development (2004) 131 (19): 4665–4675.
Published: 1 October 2004
... grow laterally but contain no endodermal component, showing that leftward growth is autonomous and independent of endoderm. In the Bapx1 –/– mutants, the SMP is defective. Normally, the SMP is a source for both Fgf9 and Fgf10; however, in the Bapx1 mutant, Fgf10 expression is downregulated...
Journal Articles
moz regulates Hox expression and pharyngeal segmental identity in zebrafish
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Journal:
Development
Development (2004) 131 (10): 2443–2461.
Published: 15 May 2004
..., mirroring the first arch pattern. bapx1 , which is normally expressed in first arch postmigratory CNC prefiguring the jaw joint, is ectopically expressed in second arch CNC of moz mutants and hox2-MO injected animals. Reduction of bapx1 function in wild types causes loss of the jaw joint. Reduction of bapx1...
Journal Articles
Bapx1 regulates patterning in the middle ear: altered regulatory role in the transition from the proximal jaw during vertebrate evolution
Available to Purchase
Journal:
Development
Development (2004) 131 (6): 1235–1245.
Published: 15 March 2004
... the ossicles to the skull. Except for the stapes, these skeletal elements are unique to mammals and are derived from the first and second branchial arches. We show that, in combination with goosecoid (Gsc), the Bapx1 gene defines the structural components of the murine middle ear. During embryogenesis, Bapx1...
Includes: Multimedia, Supplementary data
Journal Articles
Two endothelin 1 effectors, hand2 and bapx1 ,pattern ventral pharyngeal cartilage and the jaw joint
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Journal:
Development
Development (2003) 130 (7): 1353–1365.
Published: 1 April 2003
... and joints in the anterior pharyngeal arches of young larvae. Here we present genetic analyses in the zebrafish of two edn1 downstream targets, the bHLH transcription factor Hand2 and the homeobox transcription factor Bapx1, that mediate dorsoventral (DV) patterning in the anterior pharyngeal arches. First...
Journal Articles
Pax1 and Pax9 activate Bapx1 to induce chondrogenic differentiation in the sclerotome
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Journal:
Development
Development (2003) 130 (3): 473–482.
Published: 1 February 2003
... and their target genes remain to be elucidated. We show, by analyzing Pax1;Pax9 double mutant mice, that expression of Bapx1 in the sclerotome requires the presence of Pax1 and Pax9, in a gene dose-dependent manner. By using a retroviral system to overexpress Pax1 in chick presomitic mesoderm explants, we show...
Journal Articles
The murine Bapx1 homeobox gene plays a critical role in embryonic development of the axial skeleton and spleen
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Journal:
Development
Development (1999) 126 (24): 5699–5711.
Published: 15 December 1999
...Carla Tribioli; Thomas Lufkin Our previous studies in both mouse and human identified the Bapx1 homeobox gene, a member of the NK gene family, as one of the earliest markers for prechondrogenic cells that will subsequently undergo mesenchymal condensation, cartilage production and, finally...