... the abundance of bHLH factors to optimize photomorphogenesis in Arabidopsis . bHLH transcription factor E3 ubiquitin ligase Photomorphogenesis Reciprocal degradation 26S proteasome National Institutes of Health 10.13039/100000002 1R01 GM-114297 National Science Foundation...

... Summary: The transcription factor NFL acts via the GA pathway and is necessary for promoting flowering in Arabidopsis under non-inductive short-day conditions. Arabidopsis BHLH transcription factor Flowering time GA signaling pathway Photoperiod pathway Flowering is a transition...

... and musculoskeleton of the trunk and tail. The Wnt-regulated basic helix-loop-helix (bHLH) transcription factor mesogenin 1 (Msgn1) has been implicated as a cooperative regulator working in concert with T-box genes to control PSM formation in zebrafish, although the mechanism is unknown. We show here that, in mice...

.... 15 11 2013 15 5 2014 © 2014. Published by The Company of Biologists Ltd 2014 ChIP-Seq bHLH transcription factor Dorsal neural tube Neuronal subtype specification Mouse Chick Ascl1 Ptf1a The neurons within the dorsal spinal cord provide the initial integration...

... in the correct number, place and time (Guillemot, 2007 ; Pitto and Cremisi, 2010). In addition to the activity of bHLH transcription factors in determining distinct progenitor identities and regulating neurogenesis (e.g. Ben-Arie et al., 1997 ; Gazit et al., 2004 ; Guillemot, 1995), they have a role...

... Neurog2 as the first neural target of Ptf1a and revealing a bHLH transcription factor cascade functioning in the specification of GABAergic neurons in the dorsal spinal cord and cerebellum. References Beres, T., Masui, T., Swift, G. H., Shi, L., Henke, R. M. and MacDonald, R. J. (2006). PTF1...

.... * Author for correspondence (e-mail: [email protected]) 16 4 2009 © 2009. 2009 Hindbrain Math1 bHLH transcription factor Cochlear nucleus Inhibitory Excitatory Mouse Sounds received in the ear are transmitted via the auditory nerve to the cochlear nucleus (CN...

.... Firulli, A. B., McFadden, D. G., Lin, Q., Srivastava, D. and Olson, E. N. (1998). Heart and extra-embryonic mesodermal defects in mouse embryos lacking the bHLH transcription factor Hand1. Nat. Genet. 18 , 266 -270. Furness, J. B. (2000). Types of neurons in the enteric nervous system. J. Auton...

... for providing a framework to address the molecular control of neurogliogenesis and for understanding the transition of neural stem cells as they differentiate into one of the three major classes of cells in the central nervous system (CNS). Mash1 (Ascl1) bHLH transcription factor Spinal cord...

...-mail: [email protected] ; [email protected]) 31 7 2006 © 2006. 2006 bHLH transcription factor GABAergic neurons Gad65 (Gad2) Gad67 (Gad1) Megane (Heslike, Helt) Superior colliculus Midbrain Specification Mouse The GABAergic neurons are the principal inhibitory neurotransmitter...

... meiocytes are able to complete meiosis I,but they do not have a thick callose wall; they often fail to complete meiotic cytokinesis and eventually collapse. DYT1 encodes a putative bHLH transcription factor and is strongly expressed in the tapetum from late anther stage 5 to early stage 6, and at a lower...

...-mail: [email protected]) 13 10 2005 ©2005. 2005 Spinal cord development Dorsal horn inhibitory neurons BHLH transcription factor Mouse Truncation of the human PTF1A gene leads to permanent neonatal diabetes mellitus and cerebellar hypoplasia(Sellick et al., 2004), while...

...Elise Cau; Stephen W. Wilson The homeodomain transcription factor Floating head (Flh) is required for the generation of neurones in the zebrafish epiphysis. It regulates expression of two basic helix loop helix (bHLH) transcription factor encoding genes, ash1a (achaete/scute homologue 1a...

... between genes that might regulate hair cell differentiation. * Author for correspondence (e-mail: [email protected]) 09 10 2000 15 08 2000 © 2000 by Company of Biologists 2000 Cell fate determination Notch signaling bHLH transcription factor Hes Math1 Cochlea Utricle...

... is not required for rescue of primitive erythropoiesis, and infer that heterodimer formation by SCL is necessary. Our data are the first to suggest that a tissue-specific bHLH transcription factor, such as SCL, may exert powerful effects on developmental decisions without binding directly to DNA. Fig. 3...

...-mail: [email protected]) 6 April 1999 18 February 1999 © 1999 by Company of Biologists 1999 MyoD bHLH Transcription factor Myogenesis Mouse Transgenic mouse Skeletal muscle of the vertebrate body is derived from somites, paired epithelial structures formed...

... coli as fusions with glutathione-S- transferase . Gene 67 , 31 – 40 . Sommer , L. , Ma , Q. and Anderson , D. J. (1996) . neurogenins , a novel family of atonal-related bHLH transcription factors, are putative mammalian neuronal determination genes that reveal progenitor...