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Keywords: bFGF
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Journal Articles
Journal: Development
Development (2014) 141 (23): 4457–4467.
Published: 1 December 2014
... embryonic germ cells (EGCs) in culture in the presence of particular extracellular factors, such as combinations of Steel factor (KITL), LIF and bFGF (FGF2). Early PGCs form EGCs more readily than do later PGCs, and PGCs lose the ability to form EGCs by embryonic day (E) 15.5. Here, we examined the effects...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2001) 128 (14): 2629–2638.
Published: 15 July 2001
... and secondary notochord. Conversely, primary notochord precursors isolated prior to induction formed notochord in presence of BMP-4 protein. While bFGF protein had a similar activity, notochord precursors showed a different time window of competence to respond to BMP-4 and bFGF. Our data are consistent...
Journal Articles
Journal: Development
Development (1989) 107 (Supplement): 149–159.
Published: 1 April 1989
.... The evidence includes a discussion of the cell types formed in response to each type of factor, the fact that only XTCMIF (a member of the TGF-β family) and not bFGF can induce animal pole ectoderm to become Spemann's organizer, and an analysis of the timing of the gastrulation movements induced by the factors...