...Robert Fledrich; Theresa Kungl; Klaus-Armin Nave; Ruth M. Stassart ABSTRACT During the development of the peripheral nervous system, axons and myelinating Schwann cells form a unique symbiotic unit, which is realized by a finely tuned network of molecular signals and reciprocal interactions...

...Caroline C. G. Fabre; José Casal; Peter A. Lawrence The abdomen of adult Drosophila bears mechanosensory bristles with axons that connect directly to the CNS, each hemisegment contributing a separate nerve bundle. Here, we alter the amount of Engrailed protein and manipulate the Hedgehog signalling...

... or forwards direction, respectively. These two neurone classes express separate sets of genes and extend axons with oppositely directed trajectories; anterior (DA) versus posterior (DB). The DA-specific homeoprotein UNC-4 interacts with UNC-37/Groucho to repress the DB gene, acr-5 (nicotinic acetylcholine...

...Valerie A. Wallace; Martin C. Raff ABSTRACT Retinal ganglion cell (RGC) axons have been shown to stimulate the proliferation of astrocytes in the developing rodent optic nerve, but the signals that mediate this effect have not been identified. The following findings suggest that Sonic hedgehog (Shh...

...Rhona Mirsky; Cathérine Dubois; Louise Morgan; Kristján R. Jessen ABSTRACT In the rat sciatic nerve, the relationship between Schwann cells, axons, the extracellular matrix and perineurial sheath cells undergoes extensive modification between embryo day 15 and the onset of myelination during...

... development. In this study, the influence of enteric neurons on the DNA synthesis of both Schwann cells and enteric glia has been investigated as well as the effect of axonal membrane fractions (axolemma) on enteric glia. The proliferation rate of rat Schwann cells and enteric glia was assessed in culture...

...Steve Wilson; D. A. Tonge; Nigel Holder ABSTRACT Following peripheral nerve deviation in the limbs of urodele amphibians axons regrow distally toward their previous target muscles ( Holder et al . 1984 ; Proc. Roy. Soc. Lond. B 222, 477-489). This study describes analysis of this axon regeneration...