...Wenyan Mei; Zhigang Jin; Fangfang Lai; Tyler Schwend; Douglas W. Houston; Mary Lou King; Jing Yang Vertebrate axis specification is an evolutionarily conserved developmental process that relies on asymmetric activation of Wnt signaling and subsequent organizer formation on the future dorsal side...

... ligand produced from localised RNAs cooperate to initiate regionalised Wnt pathway activation. * Author for correspondence (e-mail: [email protected] ) 21 4 2008 © 2008. 2008 Wnt pathway Cnidaria Localised RNA Axis specification Canonical Wnt signalling...

... the crucial roles of Nap1/WAVE-mediated actin regulation in tissue organization and establishment of the body plan of the mammalian embryo. * Author for correspondence (e-mail: [email protected] ) 5 6 2006 © 2006. 2006 Morphogenesis Cell migration Axis specification...

... and axis specification. Secondly, it uncovers a novel role for Furin in potentiating Nodal signaling locally within the primitive endoderm and embryonic visceral endoderm during a limited time window, a function that has been masked in Furin mutants( Roebroek et al., 1998 ) due to the partially redundant...

... for correspondence (e-mail: [email protected] ) * These authors contributed equally to this work 23 7 2003 © 2003. 2003 Frat Wnt pathway Axis specification Cortical rotation Microtubules The formation of the dorsoanterior axis in Xenopus is dependent upon a series...

... of the AP axis and specification of the definitive endoderm. Targeted removal of the ASE also dramatically reduces left-sided Nodal expression, but the early events controlling LR axis specification are correctly initiated. However loss of the ASE disrupts Lefty2 ( Leftb ) expression and causes delayed...

[email protected] ) * These authors contributed equally to this paper 04 10 2000 © 1995 by Company of Biologists 1995 Axis specification Frizzled Gene targeting Mouse Wnt Wnt proteins form one of the major families of secreted ligands that play key roles in developmental...

.... * Author for correspondence (e-mail: [email protected] ) 06 04 2000 10 02 2000 © 2000 by Company of Biologists 2000 Xenopus frizzled wnt β-catenin Axis specification Dorsal mesoderm The role of wingless (wnt) protein signaling in establishment...

... . 10.1242/dev.122.5.1467 Goldstein , B. , Frisse , L. M. and Thomas , W. K. ( 1998 ). Embryonic axis specification in nematodes: evolution of the first step in development . Curr. Biol . 8 , 157 – 160 . 10.1016/S0960-9822(98)70062-4 Hill , D. P. , Shakes , D. C...

.... ( 1992 ). Reorganization of the cytoskeleton during Drosophila oogenesis: implications for axis specification and intercellular transport . Development 115 , 923 – 36 . 10.1242/dev.115.4.923 Turing , A. ( 1952 ). The chemical basis of morphogenesis . Phil. Trans. R. Soc . B...

... Axis specification no isthmus Danio rerio Splicing Generation of the large number of different cell types in the nervous system requires cell intrinsic programs and coordination between neighbouring cells. Work in recent years has established that designated cell populations exist...

... by Company of Biologists 1996 Xenopus laevis dorsal determinants cortical rotation localization axis specification Establishment of bilateral symmetry that defines the future dorsoventral axis of the embryo is an essential event of early animal development. In Xenopus , the egg...

... of asymmetrically localised cytoplasmic determinants. * Current address: Department of MCD Biology, University of Colorado, Boulder, CO 80309, USA 15 02 1996 © 1996 by Company of Biologists 1996 Caenorhabditis elegans axis specification Rhabditidae sperm fertilisation How...

... genes may be different in these early and late roles. The combined action of many Hox genes on distinct developmental processes contribute to pattern asymmetry along the A-P axis. © 1994 by Company of Biologists 1994 Hox gene limb bud morphogenesis axis specification anteroposterior...

... information retinoic acid axis specification Following amputation, adult newts are able to regenerate complete limbs. In many respects, the mechanisms under-lying control of regenerative pattern are believed to be the same as those controlling normal limb development. One major difference between...

... of retinoic acid, the level of expression in a distal blastema was not increased in comparison to controls. * Author for correspondence 19 10 1990 © 1991 by Company of Biologists 1991 homeobox limb regeneration positional information retinoic acid axis specification Limb...