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Keywords: axin1
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Journal Articles
Journal: Development
Development (2024) 151 (21): dev202899.
Published: 30 October 2024
.... However, the key genes in HERS essential for root development are understudied. Here, we show that Axin1, a scaffold protein that negatively regulates canonical Wnt signaling, is strongly expressed in the HERS. Axin1 ablation in the HERS of mice leads to defective root development, but in a manner...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (3): 479–489.
Published: 1 February 2007
... appears to act upstream of FGF signaling, which has recently been found to be essential for fin regeneration. Intriguingly, increased Wnt/β-catenin signaling is sufficient to augment regeneration, as tail fins regenerate faster in fish heterozygous for a loss-of-function mutation in axin1 , a negative...
Includes: Supplementary data