... that although the early-gastrula organizer contains cells that give rise to the axial mesoderm, the bulk of the progenitors of the head process and the notochord are localized outside the early gastrula organizer. In the mid-gastrula organizer, early gastrula organizer derived cells that are fated...

... and genetic approaches, strongly argue that nodal and nodal-related signaling molecules play a central role in axial mesodermal patterning. Mouse nodal and Xenopus nodal-related molecules are dosedependent mesoderm inducers, a finding consistent with the failure to form mesoderm in mouse embryos...

... expression reflects the function of different regions of the primitive streak and their derivatives. These studies have confirmed that mesoderm derived from the proximal primitive streak is specified appropriately. Despite the absence of a morphologically distinct node, sparse axial mesoderm cells in eed...

... of anteroposterior characteristics, although prospective prechordal plate cells may also play a role in specification of the forebrain. Hensen’s node induction neural tissue axial mesoderm somite © 1995 by Company of Biologists 1995 29 10 1994 † Present address: Department of Genetics...

... induction. Subsequently, Pintallavis is expressed in axial midline cells of all three germ layers. In axial mesoderm expression is graded with highest levels posteriorly. Midline neural plate cells that give rise to the floor plate transiently express Pin tallavis , apparently in response to induction...

...A. Ruiz i Altaba ABSTRACT The cellular mechanisms responsible for the formation of the Xenopus nervous system have been examined in total exogastrula embryos in which the axial mesoderm appears to remain segregated from prospective neural ectoderm and in recombinates of ectoderm and mesoderm...