... that a regulatory network formed by ap and dlim1 plus the homeobox genes aristaless and Bar specifies distal leg cell fates in Drosophila . We have characterised a new PD gene that encodes a protein with two Lim domains and a homeodomain, characteristic of members of the Lhx family of genes. The gene is called...

...Kerry M. Smith; Lydia Gee; Hans R. Bode ABSTRACT Developmental gradients are known to play important roles in axial patterning in hydra. Current efforts are directed toward elucidating the molecular basis of these gradients. We report the isolation and characterization of HyAlx , an aristaless...

...Takuya Tsuji; Atsushi Sato; Ichiro Hiratani; Masanori Taira; Kaoru Saigo; Tetsuya Kojima ABSTRACT During Drosophila leg development, the distal-most compartment (pretarsus) and its immediate neighbour (tarsal segment 5) are specified by a pretarsus-specific homeobox gene, aristaless , and tarsal...

... at least two different Bar functions, early antagonistic interactions with a pretarsus-specific homeobox gene, aristaless , and the subsequent induction of Fas II expression in pretarsus cells abutting tarsal segment 5. Bar homeobox genes are also required for specification of distal tarsi. Bar expression...

... chlorambucil-induced deletion allele, lst Alb , that uncovers the lst locus. Integration of the lst genetic and physical maps suggested the mouse Aristaless-like4 ( Alx4 ) gene, which encodes a paired-type homeodomain protein that plays a role in limb patterning, as a strong molecular candidate...