...-interacting proteins. One interactor, described here, is the product of the apontic gene. Coimmunoprecipitation experiments lend biochemical support to the idea that Bruno and Apontic proteins physically interact in Drosophila . Genetic experiments using mutants defective in apontic and bruno reveal...

... for the development of a subset of embryonic Dfd -dependent structures, while leaving many other segmental structures intact. We cloned and characterized one of these two, which we have named apontic ( apt ). apt is required for the elaboration of dorsal and ventral head structures. It encodes a 484-amino-acid...