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Keywords: aphidicolin
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Journal Articles
Journal Articles
Journal: Development
Development (1991) 112 (2): 559–569.
Published: 1 June 1991
...Martha B. Rollins; Matthew T. Andrews ABSTRACT Xenopus embryos were transferred into media containing aphidicolin at late blastula, mid-gastrula, and early neurula stages. In each case, embryos continued to differentiate in the absence of DNA replication. When the inhibitor was added at late...
Journal Articles
Journal: Development
Development (1987) 99 (3): 429–437.
Published: 1 March 1987
... studies revealed that a dose of 1000 rad reduced DNA synthesis of mid and late 12-day glands by 72 and 65 %, respectively. Histological examination of X-irradiated late 12-day gland showed that mitotic figures were rarely seen in the epithelium at 6 h of culture. Aphidicolin, a specific inhibitor of DNA...
Journal Articles
Journal: Development
Development (1985) 89 (1): 133–148.
Published: 1 October 1985
...Roger K. W. Smith; Martin H. Johnson ABSTRACT The effects of aphidicolin, a reversible inhibitor of DNA polymerase alpha, both on replication and on development of the mouse embryo from the 2- and 4-cell stages to the compacted late 8-cell stage have been assessed. The continuous presence...