... that movement of injected RNA in embryos appears much faster than that in oocytes, however, the rapid divisions ensure segregation of injected RNAs. This poses problems for experiments involving injections of sense or anti-sense RNA since homogenous distribution throughout the embryo may be a desired objective...

... for the function of the cloned genes. We have explored the possibility of studying gene function by preventing the expression of the gene product in vivo by injecting anti-sense RNA. This report summarizes our recent efforts to prevent mRNA translation in vivo by injecting RNA that is complementary to messenger...