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Keywords: acn-1
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Journal Articles
Brian M. Egan, Franziska Pohl, Xavier Anderson, Shoshana C. Williams, Imienreluefe Gregory Adodo, Patrick Hunt, Zuoxu Wang, Chen-Hao Chiu, Andrea Scharf, Matthew Mosley, Sandeep Kumar, Daniel L. Schneider, Hideji Fujiwara, Fong-Fu Hsu, Kerry Kornfeld
Journal:
Development
Development (2024) 151 (3): dev202146.
Published: 12 February 2024
... gene, a powerful regulator of aging. The homologous mutation in the human insulin receptor causes Donohue syndrome, establishing these mutant worms as an invertebrate model of this disease. Captopril functions in C. elegans by inhibiting ACN-1, the worm homolog of ACE. Reducing the activity of acn-1...
Includes: Supplementary data
