... and Cebpa ) are increased. In vitro, p45NF-E2 deficiency results in spontaneous syncytiotrophoblast formation, which can be reversed by Gcm1 knockdown. Increased Gcm1 expression in the absence of p45NF-E2 is dependent on enhanced protein acetylation, including post-translational modification of Gcm1...

... target genes, whereas acetylation of H3K27 (H3K27ac) has recently been shown to be associated with many active mammalian genes. The Trithorax protein (TRX),which associates with the histone acetyltransferase CBP, is required for maintenance of transcriptionally active states and antagonizes Polycomb...

... 08 12 1997 © 1998 by Company of Biologists 1998 Gene silencing Trichostatin A Genomic imprinting Position-effect variegation Allele-specific in situ hybridisation Mouse H19 Acetylation Histone Cell- and tissue-specific transcriptional silencing is a characteristic...

... of asymmetrical cell division and the changes in cellular organisation taking place during epithelial differentiation. * Author for correspondence Copyright © 1991 by Company of Biologists 1991 microtubule post-translational modifications acetylation centriole polarity asymmetric division...