... and performed gene expression profiling to identify potential ISC regulators. A detailed analysis of one of these potential regulators, the zinc-finger protein Charlatan, was carried out. MARCM clonal analysis and RNAi in precursor cells showed that loss of Chn function caused severe ISC division defects...

... could have arisen from an ancestral limb with an unsegmented tarsus. * Author for correspondence (e-mail: [email protected] ) 27 8 2003 © 2003. 2003 Limb development Tarsus Drosophila Notch odd-skipped Zinc-finger protein Animal limbs develop...

...Shiuh-Wen Luoh; Paul A. Bain; Roberto D. Polakiewicz; Mary L. Goodheart; Humphrey Gardner; Rudolf Jaenisch; David C. Page ABSTRACT The zinc-finger proteins ZFX and ZFY, encoded by genes on the mammalian X and Y chromosomes, have been spec-ulated to function in sex differentiation, spermatogenesis...

...Brian P. Zambrowicz; James W. Zimmermann; Christopher J. Harendza; Elizabeth M. Simpson; David C. Page; Ralph L. Brinster; Richard D. Palmiter ABSTRACT The Zfy-1 and Zfy-2 genes, which arose by gene duplication, map to the mouse Y chromosome and encode nearly identical zinc-finger proteins. Zfy-1...

... into two domains, as well as an acidic domain. These features suggest that Evi-1 encodes a transcriptional regulatory protein. In Drosophila , zinc-finger proteins such as Kruppel are involved in body plan patterning, and exhibit a spatially restricted pattern of expression in the embryo. To determine...