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Keywords: Zebrafish mutant
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Journal Articles

The Paf1 complex and P-TEFb have reciprocal and antagonist roles in maintaining multipotent neural crest progenitors

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Michael J. Jurynec, Xiaoying Bai, Brent W. Bisgrove, Haley Jackson, Alex Nechiporuk, Rebecca A. S. Palu, Hannah A. Grunwald, Yi-Chu Su, Kazuyuki Hoshijima, H. Joseph Yost, Leonard I. Zon, David Jonah Grunwald
Journal: Development
Development (2019) 146 (24): dev180133.
https://doi.org/10.1242/dev.180133
Published: 16 December 2019
...-associated factor 1 complex function is required to maintain the neural crest progenitor population in zebrafish. Paf1 complex Neural crest Stem cells Transcription pausing Zebrafish mutant P-TEFb National Institutes of Health 10.13039/100000002 1P01HD048886 1R01HD081950 P30CA042014...
View articletitled, The Paf1 complex and P-TEFb have reciprocal and antagonist roles in maintaining multipotent neural crest progenitors
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Includes: Supplementary data
Journal Articles

Specification of hematopoietic and vascular development by the bHLH transcription factor SCL without direct DNA binding

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Catherine Porcher, Eric C. Liao, Yuko Fujiwara, Leonard I. Zon, Stuart H. Orkin
Journal: Development
Development (1999) 126 (20): 4603–4615.
https://doi.org/10.1242/dev.126.20.4603
Published: 15 October 1999
... and vascular development in vertebrates. Contrary to all expectation, we find that SCL variants unable to bind DNA rescue hematopoiesis from gene-targeted SCL −/− embryonic stem cells and complement hematopoietic and vascular deficits in the zebrafish mutant cloche . Our findings establish DNA-binding...
View articletitled, Specification of hematopoietic and vascular development by the bHLH transcription factor SCL without direct DNA binding
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