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Keywords: ZEB
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Journal Articles

Inhibition of cell fate repressors secures the differentiation of the touch receptor neurons of Caenorhabditis elegans

Chaogu Zheng, Felix Qiaochu Jin, Brian Loeber Trippe, Ji Wu, Martin Chalfie
Journal: Development
Development (2018) 145 (22): dev168096.
https://doi.org/10.1242/dev.168096
Published: 15 November 2018
... neurons fail to activate TRN genes, however, because a complex of two transcriptional repressors (EGL-44/EGL-46) prevents their expression. Here, we show that the ZEB family transcriptional factor ZAG-1 promotes TRN differentiation not by activating TRN genes but by preventing the expression of EGL-44/EGL...
View article titled, Inhibition of cell fate repressors secures the differentiation of the touch receptor neurons of Caenorhabditis elegans
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Includes: Supplementary data
Journal Articles

miR-200 and miR-96 families repress neural induction from human embryonic stem cells

Zhong-Wei Du, Li-Xiang Ma, Christian Phillips, Su-Chun Zhang
Journal: Development
Development (2013) 140 (12): 2611–2618.
https://doi.org/10.1242/dev.092809
Published: 15 June 2013
...), but not to epidermal (EPI) cells and found that two miRNA families, miR-200 and miR-96, were uniquely downregulated in the NEP cells. We confirmed zinc-finger E-box-binding homeobox (ZEB) transcription factors as a target of the miR-200 family members and identified paired box 6 (PAX6) transcription factor as the new...
View article titled, miR-200 and miR-96 families repress neural induction from human embryonic stem cells
Open the PDF for miR-200 and miR-96 families repress neural induction from human embryonic stem cells in another window
Includes: Supplementary data