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Journal Articles

YAC complementation shows a requirement for Wt1 in the development of epicardium, adrenal gland and throughout nephrogenesis

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Adrian W. Moore, Lesley McInnes, Jordan Kreidberg, Nicholas D. Hastie, Andreas Schedl
Journal: Development
Development (1999) 126 (9): 1845–1857.
https://doi.org/10.1242/dev.126.9.1845
Published: 1 May 1999
... a lacZ reporter gene inserted into a YAC construct, we demonstrate that WT1 is expressed in the early proepicardium, the epicardium and the subepicardial mesenchymal cells (SEMC). Lack of WT1 leads to severe defects in the epicardial layer and a concomitant absence of SEMCs, which explains...
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