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Keywords: X-inactivation
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Journal Articles
Journal: Development
Series: REVIEW COMMONS TRANSFER
Development (2022) 149 (9): dev200568.
Published: 6 May 2022
.... , Nora , E. , Guggiari , M. , Maresca , M. , Stewart , A. F. and Heard , E. ( 2007 ). Sensing X chromosome pairs before X inactivation via a novel X-pairing region of the Xic . Science 318 , 1632 - 1636 . 10.1126/science.1149420 Augui , S. , Nora , E. P...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (13): 2649–2659.
Published: 1 July 2011
...Yuko Hoki; Rieko Ikeda; Nathan Mise; Yuka Sakata; Tatsuya Ohhata; Hiroyuki Sasaki; Kuniya Abe; Takashi Sado X chromosome inactivation (X-inactivation) in female mammals is triggered by differential upregulation of the Xist gene on one of the two X chromosomes and subsequent coating of the X in cis...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (1): 139–146.
Published: 1 January 2009
...Yuko Hoki; Naomi Kimura; Minako Kanbayashi; Yuko Amakawa; Tatsuya Ohhata; Hiroyuki Sasaki; Takashi Sado X-inactivation in female mammals is triggered by the association of non-coding Xist RNA in cis with the X chromosome. Although it has been suggested that the A-repeat located in the proximal part...
Journal Articles
Journal: Development
Development (2006) 133 (24): 4925–4931.
Published: 15 December 2006
...Takashi Sado; Yuko Hoki; Hiroyuki Sasaki Dosage differences of X-linked genes between male and female mammals are compensated for by a mechanism known as X-inactivation, and the noncoding Xist gene plays a crucial role in this process. The expression of Xist is regulated in cis by its noncoding...
Journal Articles
Journal: Development
Development (2005) 132 (7): 1649–1661.
Published: 1 April 2005
... of the epiblast or trophoblast. Chimeras generated by injection of XEN cells into blastocysts showed exclusive contribution to extra-embryonic endoderm cell types. We used female XEN cells to investigate the mechanism of X chromosome inactivation in this lineage. We observed paternally imprinted X-inactivation...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2003) 130 (18): 4235–4248.
Published: 15 September 2003
... transiently to one X chromosome in female embryos at the onset of X-inactivation. This accumulation and the associated histone methylation are also lost in Ezh2 mutants, suggesting a role in X inactivation. Thus,Ezh2 has significant and diverse roles during early development, as well as during...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2002) 129 (2): 479–492.
Published: 15 January 2002
... of the hermaphrodite X chromosome is reminiscent of asymmetries observed for the human X chromosome in the female soma. The arm of the X chromosome which contains the X-inactivation center, Xq, is enriched for interspersed repeated LINE-1 elements which themselves are enriched in α-heterochromatin ( Bailey et al...
Journal Articles
Journal: Development
Development (1990) 108 (Supplement): 35–45.
Published: 1 April 1990
... certain genes become heterochromatically repressed. Key words: Drosophila, position effect variegation, X- inactivation, chromosome imprinting, heterochromatin, mass action, macromolecular assembly, gene dosage effects. Introduction By following chromosomes through their division cycles, Heitz (1928, 1929...
Journal Articles
Journal: Development
Development (1987) 101 (Supplement): 119–125.
Published: 1 March 1987
... with the 12E7 antigen. These molecular tools have been used to investigate the genetics and biochemistry of the MIC2 system. Recent results suggest that MIC2 is the most proximal of the currently defined pseudoautosomal markers and that the escape of MIC2 from X-inactivation may be intrinsic to an associated...
Journal Articles
Journal: Development
Development (1986) 97 (Supplement): 257–262.
Published: 1 October 1986
... a small multigene family with the evolutionarily related serum albumin gene (Gorin et al . 1980; Ingram, Scott & Tilghman, 1981). Copyright © 1986 by Company of Biologists 1986 transgenic mice AFP gene gene regulation X-inactivation mouse germlin α-foetoprotein J. Embryol. exp. Morph...
Journal Articles
Journal: Development
Development (1986) 96 (1): 295–302.
Published: 1 July 1986
... words: X-inactivation, mosaics, pigmentation, genetic activity, Cattanach's insertion, albino, mouse, mutation. 296 M. S. DEOL, G. M. TRUSLOVE AND A. MCLAREN It was found that in such animals the albino (cc) patches have a strong tendency to grow darker with age, as if there were reversal...