...Eric Wieschaus; Dari Sweeton ABSTRACT To examine the requirements for X-chromosomal transcription during precellular stages of Drosophila embryogenesis, attached X-chromosomes and XY translocations were used to generate embryos deficient for large cytologically defined regions of that chromosome...

...-chromosomally localized to Xql3–q21.1, using anonymous probe DXYS1; a LOD score of 3· 07 was obtained. We are preparing cosmid libraries from DNA from mouse cell lines containing only the relevant part of the human X chromosome, introduced by chromosome-mediated gene transfer. Cosmids that contain human X...

...Mary F. Lyon; J. Zenthon; E. P. Evans; M. D. Burtenshaw; Kathryn A. Wareham; E. D. Williams ABSTRACT Previous evidence had shown that, when a mammalian X-chromosome is broken by a translocation, only one of the two X-chromosome segments shows cytological signs of X-inactivation in the form of late...