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Keywords: X chromosome inactivation
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Journal Articles
Journal: Development
Development (2022) 149 (22): dev200845.
Published: 28 November 2022
... with their in vitro culture have resulted in an under-representation of female mESCs in the literature. Recent studies show that the second X chromosome in female, and more specifically the transcriptional activity from both of these chromosomes due to absent X chromosome inactivation, sets female and male mESCs...
Includes: Supplementary data
Journal Articles
Journal: Development
Series: REVIEW COMMONS TRANSFER
Development (2022) 149 (15): dev200864.
Published: 2 August 2022
... , 17450 - 17455 . 10.1073/pnas.0408021101 Chaumeil , J. , Waters , P. D. , Koina , E. , Gilbert , C. , Robinson , T. J. and Graves , J. A. M. ( 2011 ). Evolution from XIST-independent to XIST-controlled X-chromosome inactivation: epigenetic modifications in distantly...
Includes: Supplementary data
Journal Articles
In collection:
Human development
Journal: Development
Development (2020) 147 (1): dev183095.
Published: 3 January 2020
...Catherine Patrat; Jean-François Ouimette; Claire Rougeulle ABSTRACT X chromosome inactivation (XCI) is a key developmental process taking place in female mammals to compensate for the imbalance in the dosage of X-chromosomal genes between sexes. It is a formidable example of concerted gene...
Journal Articles
Journal: Development
Development (2017) 144 (15): 2784–2797.
Published: 1 August 2017
... of Biologists Ltd 2017 http://www.biologists.com/user-licence-1-1/ Highlighted article: The genome-wide impact of Xist RNA lacking the A-repeat suggests a significant role for Xist in gene regulation beyond imprinted X inactivation. X chromosome inactivation Xist RNA Trophoblast...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (16): 2958–2964.
Published: 15 August 2016
... in vivo. X chromosome reactivation X chromosome inactivation Live-cell imaging Pluripotent stem cells Early mouse development Silencing of one of the two X chromosomes in female mammals is an epigenetic gene regulatory mechanism known as X chromosome inactivation (XCI). The patterns...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (12): 2085–2089.
Published: 15 June 2012
.... Depending on the developmental time window, imprinted or random X chromosome inactivation (XCI) is initiated, and both processes lead to an inactive X chromosome that is clonally inherited. Here, we review new insights into the life cycle of XCI and provide an overview of the mechanisms regulating X...
Journal Articles
Journal: Development
Development (2012) 139 (12): 2130–2138.
Published: 15 June 2012
...Joshua W. Mugford; Della Yee; Terry Magnuson Proper regulation of X-linked gene expression, termed dosage compensation, is required for the normal development of mammalian embryos. Through the process of X chromosome inactivation (XCI), somatic cells of mammalian females inactivate one of their two...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (5): 975–982.
Published: 1 March 2004
... for correspondence (e-mail: tsado@lab.nig.ac.jp ) 12 11 2003 © 2004. 2004 X chromosome inactivation De novo DNA methyltransferases Xist It is well known that DNA methylation plays an important role(s) in the regulation of gene expression, maintenance of genomic integrity, parental...