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Keywords: X chromosome inactivation
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Journal Articles
Journal: Development
Development (2022) 149 (22): dev200845.
Published: 28 November 2022
... with their in vitro culture have resulted in an under-representation of female mESCs in the literature. Recent studies show that the second X chromosome in female, and more specifically the transcriptional activity from both of these chromosomes due to absent X chromosome inactivation, sets female and male mESCs...
Includes: Supplementary data
Journal Articles
Journal: Development
Series: REVIEW COMMONS TRANSFER
Development (2022) 149 (15): dev200864.
Published: 2 August 2022
... by The Company of Biologists Ltd 2022 Summary: Absence of SmcHD1 in mouse epiblast stem cells and embryonic fibroblasts leads to a loss of histone H3K9me3 enrichment on the inactive X chromosome, revealing a crucial role of SmcHD1 in X chromosome inactivation. X chromosome inactivation...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (1): dev183095.
Published: 3 January 2020
...Catherine Patrat; Jean-François Ouimette; Claire Rougeulle ABSTRACT X chromosome inactivation (XCI) is a key developmental process taking place in female mammals to compensate for the imbalance in the dosage of X-chromosomal genes between sexes. It is a formidable example of concerted gene...
Journal Articles
Journal: Development
Development (2017) 144 (15): 2784–2797.
Published: 1 August 2017
... of Biologists Ltd 2017 http://www.biologists.com/user-licence-1-1/ Highlighted article: The genome-wide impact of Xist RNA lacking the A-repeat suggests a significant role for Xist in gene regulation beyond imprinted X inactivation. X chromosome inactivation Xist RNA Trophoblast...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2012) 139 (12): 2085–2089.
Published: 15 June 2012
.... Depending on the developmental time window, imprinted or random X chromosome inactivation (XCI) is initiated, and both processes lead to an inactive X chromosome that is clonally inherited. Here, we review new insights into the life cycle of XCI and provide an overview of the mechanisms regulating X...
Journal Articles
Journal: Development
Development (2012) 139 (12): 2130–2138.
Published: 15 June 2012
...Joshua W. Mugford; Della Yee; Terry Magnuson Proper regulation of X-linked gene expression, termed dosage compensation, is required for the normal development of mammalian embryos. Through the process of X chromosome inactivation (XCI), somatic cells of mammalian females inactivate one of their two...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (1998) 125 (17): 3353–3363.
Published: 1 September 1998
... trophectoderm derivatives (ectoplacental cone and extraembryonic ectoderm) are severely affected, but the primitive endoderm derivatives (visceral and parietal endoderm) are relatively unaffected. Successful rescue of DsX M embryos by aggregation with tetraploid embryos show that X chromosome inactivation...
Journal Articles
Journal: Development
Development (1995) 121 (4): 1029–1039.
Published: 1 April 1995
... 12 1994 © 1995 by Company of Biologists 1995 cerebral cortex mouse clonal analysis genetic mosaics X chromosome inactivation During early development, neurons in the mammalian cerebral cortex are generated in a proliferative layer known as the ventricular zone ( Boulder...
Journal Articles
Journal: Development
Development (1994) 120 (12): 3529–3536.
Published: 1 December 1994
... and differentiating (XX) ES cells are compatible only with models that do not require Xist RNA to cover the entire inactive X chromosome. 20 09 1994 © 1994 by Company of Biologists 1994 ES cells X chromosome inactivation imprinting allele-specific assays mouse RNA Xist X chromosome...
Journal Articles
Journal: Development
Development (1992) 116 (3): 687–695.
Published: 1 November 1992
... of Molecular Biology, Austrian Academy of Sciences, A-5020 Salzburg, Billrothstrasse 11, Austria † Department of Physiology, Colorado State University, Fort Collins, CO 80523, USA 04 08 1992 © 1992 by Company of Biologists 1992 X chromosome inactivation transgenic mice type I...
Journal Articles
Journal: Development
Development (1990) 110 (3): 969–975.
Published: 1 November 1990
...-inactivation in progenitors of extraembryonic membranes. * Present address: Department of Biology, Shandong Medical University, Jinan, China † Author for correspondence 21 08 1990 © 1990 by Company of Biologists 1990 X chromosome inactivation mouse development polar...