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Keywords: Wwtr1
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Journal Articles
The Hippo pathway effector Wwtr1 regulates cardiac wall maturation in zebrafish
Available to PurchaseJason K. H. Lai, Michelle M. Collins, Veronica Uribe, Vanesa Jiménez-Amilburu, Stefan Günther, Hans-Martin Maischein, Didier Y. R. Stainier
Journal:
Development
Development (2018) 145 (10): dev159210.
Published: 17 May 2018
... been implicated in cardiac development but many questions remain. We have investigated the role of Wwtr1, a nuclear effector of the Hippo pathway, in zebrafish and find that its loss leads to reduced cardiac trabeculation. However, in mosaic animals, wwtr1 −/− cardiomyocytes contribute more frequently...
Includes: Supplementary data
Journal Articles
Loss of Mob1a/b in mice results in chondrodysplasia due to YAP1/TAZ-TEAD-dependent repression of SOX9
Available to PurchaseHiroki Goto, Miki Nishio, Yoko To, Tatsuya Oishi, Yosuke Miyachi, Tomohiko Maehama, Hiroshi Nishina, Haruhiko Akiyama, Tak Wah Mak, Yuma Makii, Taku Saito, Akihiro Yasoda, Noriyuki Tsumaki, Akira Suzuki
Journal:
Development
Development (2018) 145 (6): dev159244.
Published: 16 March 2018
.../0092-8674(94)90041-8 Wang , X. , Zheng , Z. , Caviglia , J. M. , Corey , K. E. , Herfel , T. M. , Cai , B. , Masia , R. , Chung , R. T. , Lefkowitch , J. H. , Schwabe , R. F. , et al. ( 2016 ). Hepatocyte TAZ/WWTR1 promotes inflammation and fibrosis...
Includes: Supplementary data
Journal Articles
Wnt/β-catenin signaling via Axin2 is required for myogenesis and, together with YAP/Taz and Tead1, active in IIa/IIx muscle fibers
Available to PurchaseDanyil Huraskin, Nane Eiber, Martin Reichel, Laura M. Zidek, Bojana Kravic, Dominic Bernkopf, Julia von Maltzahn, Jürgen Behrens, Said Hashemolhosseini
Journal:
Development
Development (2016) 143 (17): 3128–3142.
Published: 1 September 2016
... is implicated in myotube formation and, together with YAP/Taz/Tead1, is associated with reduced muscle fiber diameter of a subset of fast fibers. Axin2 Yap1 Wwtr1 Tead1 Skeletal muscle Muscle fibers Satellite cells The Wnt gene family encodes 19 secreted glycoproteins, which bind...
Includes: Supplementary data
Journal Articles
Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators
Available to Purchase
Journal:
Development
Development (2013) 140 (16): 3323–3334.
Published: 15 August 2013
... progenitor pool, suggesting that Nf2 limits the expansion of neural progenitor populations during brain development. Through molecular and genetic approaches, we demonstrate that Nf2 functions by inhibiting the transcriptional coactivators Yap (Yap1 - Mouse Genome Informatics) and Taz (Wwtr1 - Mouse Genome...
Includes: Supplementary data
