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Date
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1-20 of 29
Keywords: Wound healing
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Journal Articles
Jake Turley, Francesca Robertson, Isaac V. Chenchiah, Tanniemola B. Liverpool, Helen Weavers, Paul Martin
Journal:
Development
Development (2024) 151 (18): dev202943.
Published: 24 September 2024
...Jake Turley; Francesca Robertson; Isaac V. Chenchiah; Tanniemola B. Liverpool; Helen Weavers; Paul Martin ABSTRACT One of the key tissue movements driving closure of a wound is re-epithelialisation. Earlier wound healing studies describe the dynamic cell behaviours that contribute to wound re...
Includes: Supplementary data
Journal Articles
Journal:
Development
Development (2023) 150 (5): dev201231.
Published: 9 March 2023
.... Highlighted Article: EGF receptor signaling in Drosophila protects epithelial tissues under mechanical stress from collapsing by preventing apical cell extrusion. Morphogenesis Invagination Apoptosis Wound healing Vitelline membrane Epidermal growth factor signaling RIKEN http...
Includes: Supplementary data
Journal Articles
Embracing the diversity of model systems to deconstruct the basis of regeneration and tissue repair
Free
Journal:
Development
Development (2023) 150 (3): dev201579.
Published: 31 January 2023
... in deciphering the molecular and cellular basis of wound healing, tissue repair and regeneration, as well as their implications for future clinical applications. The conference showcased an ever-expanding diversity of model organisms used to identify mechanisms that promote regeneration. Over 25 species were...
Journal Articles
In collection:
Review Commons Transfers
Tomoaki Iwayama, Mizuho Iwashita, Kazuya Miyashita, Hiromi Sakashita, Shuji Matsumoto, Kiwako Tomita, Phan Bhongsatiern, Tomomi Kitayama, Kentaro Ikegami, Takashi Shimbo, Katsuto Tamai, Masanori A. Murayama, Shuhei Ogawa, Yoichiro Iwakura, Satoru Yamada, Lorin E. Olson, Masahide Takedachi, Shinya Murakami
Journal:
Development
Series: REVIEW COMMONS TRANSFER
Development (2022) 149 (19): dev201203.
Published: 17 October 2022
... to the lack of efficient methods to isolate PDLCs and other cells from the PDL. Future studies should elucidate how pericytes and PDLCs repair tissues by interacting with immune cells at each stage of wound healing. Other cell types, such as plasma cells, which were not analyzed in this study ( Fig. S4C...
Includes: Supplementary data
Journal Articles
Colonic healing requires Wnt produced by epithelium as well as Tagln + and Acta2 + stromal cells
FreeSoumyashree Das, Qiang Feng, Iyshwarya Balasubramanian, Xiang Lin, Haoran Liu, Oscar Pellón-Cardenas, Shiyan Yu, Xiao Zhang, Yue Liu, Zhi Wei, Edward M. Bonder, Michael P. Verzi, Wei Hsu, Lanjing Zhang, Timothy C. Wang, Nan Gao
Journal:
Development
Development (2022) 149 (1): dev199587.
Published: 12 January 2022
... Wound healing Intestinal stem cell National Institutes of Health R01DK102934 R01DE026936 R01DE015654 R01DK119198 R01AT010243 American Cancer Society http://dx.doi.org/10.13039/100000048 RSG-15-060-01-TBE National Science Foundation http://dx.doi.org/10.13039...
Includes: Supplementary data
Journal Articles
Parallels between wound healing, epimorphic regeneration and solid tumors
Available to Purchase
Journal:
Development
Development (2020) 147 (1): dev181636.
Published: 2 January 2020
...Alan Y. Wong; Jessica L. Whited ABSTRACT Striking similarities between wound healing, epimorphic regeneration and the progression of solid tumors have been uncovered by recent studies. In this Review, we discuss systemic effects of tumorigenesis that are now being appreciated in epimorphic...
Journal Articles
Ectodysplasin-A signaling is a key integrator in the lacrimal gland–cornea feedback loop
Available to Purchase
Journal:
Development
Development (2019) 146 (14): dev176693.
Published: 16 July 2019
... injury. This observation hints towards a role for the Eda pathway in controlling the switch from basal to reflex tears, to support corneal wound healing. Collectively, our data suggest a crucial implication of Eda signaling in the cornea–lacrimal gland feedback loop, both in physiological...
Includes: Supplementary data
Journal Articles
Repair, regenerate and reconstruct: meeting the state-of-the-art
Available to Purchase
Journal:
Development
Development (2019) 146 (9): dev176974.
Published: 8 May 2019
... advances in wound healing, repair and regeneration. The meeting covered a wide range of regeneration models and tissues, identification of regulatory genes and signals, and striking advances toward regenerative therapies. Here, we report some of the exciting topics discussed during this conference...
Journal Articles
Non-apoptotic function of Drosophila caspase activation in epithelial thorax closure and wound healing
Available to Purchase
Journal:
Development
Development (2019) 146 (4): dev169037.
Published: 15 February 2019
... taken place. Further genetic analysis revealed that the activation of the initiator caspase Dronc is coupled with the generation of reactive oxygen species. The activation of Dronc also regulates myosin levels and delays wound healing. Our findings suggest a possible function for non-apoptotic caspase...
Includes: Supplementary data
Journal Articles
David E. Reichman, Laura Park, Limor Man, David Redmond, Kenny Chao, Richard P. Harvey, Makoto M. Taketo, Zev Rosenwaks, Daylon James
Journal:
Development
Development (2018) 145 (1): dev159905.
Published: 8 January 2018
... inhibitory Wnt signaling via Wnt5a fosters endothelial differentiation of Nkx2.5 + cardiac progenitor cells during mouse embryogenesis and human pluripotent stem cell differentiation. Cardiac development Cardiac differentiation Wound healing Myocardial infarction Myocardial scar formation...
Includes: Supplementary data
Journal Articles
Trends in tissue repair and regeneration
Available to Purchase
Journal:
Development
Development (2017) 144 (3): 357–364.
Published: 1 February 2017
... and highlights the diversity of regeneration strategies in different organ systems and species. Cell plasticity and cell reprogramming Blastema dynamics Model systems Immune response Transcriptional control of regeneration Wound healing Injury-induced signaling Senescence and ageing Canton...
Journal Articles
Beryllium nitrate inhibits fibroblast migration to disrupt epimorphic regeneration
Available to Purchase
Journal:
Development
Development (2016) 143 (19): 3491–3505.
Published: 1 October 2016
... by The Company of Biologists Ltd 2016 Summary: Inhibiting fibroblast migration during regeneration in axolotl reveals the importance of fibroblasts for blastema-based limb regeneration but not non-blastemal skin regrowth. Beryllium Regeneration Wound healing Limb development Ambystoma...
Includes: Supplementary data
Journal Articles
Re-epithelialization of cutaneous wounds in adult zebrafish combines mechanisms of wound closure in embryonic and adult mammals
Available to PurchaseRebecca Richardson, Manuel Metzger, Philipp Knyphausen, Thomas Ramezani, Krasimir Slanchev, Christopher Kraus, Elmon Schmelzer, Matthias Hammerschmidt
Journal:
Development
Development (2016) 143 (12): 2077–2088.
Published: 15 June 2016
... cellular processes that take place both within the epidermis and in other participating tissues. Re-epithelialization of partial- or full-thickness skin wounds of adult zebrafish, however, is extremely rapid and largely independent of the other processes of wound healing. Live imaging after treatment...
Includes: Supplementary data
Journal Articles
Primary cilia maintain corneal epithelial homeostasis by regulation of the Notch signaling pathway
Available to Purchase
Journal:
Development
Development (2016) 143 (12): 2160–2171.
Published: 15 June 2016
... Notch signaling and cell proliferation to maintain normal epithelial thickness. Primary cilia Cornea Ocular surface Notch signaling Epithelium Wound healing Mouse The outermost layer of the cornea consists of a stratified non-keratinized pseudosquamous epithelium known as corneal...
Includes: Supplementary data
Journal Articles
Essential elements for translation: the germline factor Vasa functions broadly in somatic cells
Available to Purchase
Journal:
Development
Development (2015) 142 (11): 1960–1970.
Published: 1 June 2015
... is essential for: (1) general mRNA translation during embryogenesis, (2) developmental re-programming upon manipulations to the embryo and (3) larval wound healing. We also learned that Vasa interacted with mRNAs in the perinuclear area and at the spindle in an Importin-dependent manner during cell cycle...
Includes: Supplementary data
Journal Articles
Automated multidimensional image analysis reveals a role for Abl in embryonic wound repair
Available to Purchase
Journal:
Development
Development (2014) 141 (14): 2901–2911.
Published: 15 July 2014
... is remarkable in embryos, in which epidermal wounds heal rapidly, with little inflammation and no scarring ( Rowlatt, 1979 ). The rapid embryonic response to wounds is conserved across species, from fruit flies to humans ( Longaker et al., 1990 ; McCluskey and Martin, 1995 ; Rowlatt, 1979 ; Whitby...
Includes: Supplementary data
Journal Articles
Journal:
Development
Development (2014) 141 (9): 1814–1820.
Published: 1 May 2014
.../licenses/by/3.0 ), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. Wound healing Drosophila embryo Actomyosin behaviour Throughout embryonic development, individual epithelial cells divide, stretch...
Includes: Supplementary data
Journal Articles
Intradermal adipocytes mediate fibroblast recruitment during skin wound healing
Available to Purchase
Journal:
Development
Development (2013) 140 (7): 1517–1527.
Published: 1 April 2013
...Barbara A. Schmidt; Valerie Horsley Acute wound healing in the skin involves the communication of multiple cell types to coordinate keratinocyte and fibroblast proliferation and migration for epidermal and dermal repair. Many studies have focused on the interplay between hematopoietic cells...
Includes: Supplementary data
Journal Articles
Lhx2 differentially regulates Sox9, Tcf4 and Lgr5 in hair follicle stem cells to promote epidermal regeneration after injury
Available to PurchaseAndrei N. Mardaryev, Natalia Meier, Krzysztof Poterlowicz, Andrey A. Sharov, Tatyana Y. Sharova, Mohammed I. Ahmed, Valentina Rapisarda, Christopher Lewis, Michael Y. Fessing, Thomas M. Ruenger, Jag Bhawan, Sabine Werner, Ralf Paus, Vladimir A. Botchkarev
Journal:
Development
Development (2011) 138 (22): 4843–4852.
Published: 15 November 2011
.... 217 , 206 – 216 . Ansell D. M. , Kloepper J. E. , Thomason H. A. , Paus R. , Hardman M. J. ( 2011 ). Exploring the ‘hair growth-wound healing connection’: anagen phase promotes wound re-epithelization . J. Invest. Dermatol. 131 , 512 – 528 . Blanpain C...
Includes: Supplementary data
Journal Articles
Necl2 regulates epidermal adhesion and wound repair
Available to Purchase
Journal:
Development
Development (2009) 136 (20): 3505–3514.
Published: 15 October 2009
...,and inhibition of cell motility and in vitro wound healing. Although the rate of cell proliferation was reduced, terminal differentiation was unaffected. To assess the role of Necl2 in vivo, we examined the epidermis of Necl2 -null mice and developed transgenic mice that expressed Necl2 in the basal layer...
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