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Keywords: Wnt2b
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Journal Articles
Journal: Development
Development (2018) 145 (21): dev163212.
Published: 2 November 2018
... found that the Wnt pathway, which directs peripheral retinal differentiation and, generally, cell proliferation, is dysregulated in the albino RPE. Wnt2b expression is expanded in the albino RPE compared with the pigmented RPE, and the expanded region adjoins the site of ipsilateral RGC neurogenesis...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2006) 133 (16): 3167–3177.
Published: 15 August 2006
... that the expression of Wnt2b or constitutively active (CA) β-catenin inhibited retinal progenitor gene(RPG) expression and the differentiation of retinal neurons. In addition, Wnt signal activation in the central retina was sufficient to induce the expression of markers of the ciliary body and iris, two tissues...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (15): 2805–2815.
Published: 1 August 2006
... regulatory hierarchy has not been determined in any species. tbx5 is the earliest gene expressed in the limb bud mesenchyme. Recently, another transcription factor, Prdm1, has been shown to be crucial for zebrafish forelimb development. Here, we show that Prdm1 is downstream of RA, Wnt2b and Tbx5 activity...
Journal Articles
Journal: Development
Development (2003) 130 (15): 3515–3524.
Published: 1 August 2003
..., is thought to initiate forelimb formation by activating wnt2b , which then induces the expression of tbx5 in the adjacent lateral plate mesoderm. Tbx5, in turn, is required for the activation of fgf10 , which relays the limb inducing signal to the overlying ectoderm. We show that the zebrafish fgf24 gene...
Journal Articles
Journal Articles