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Keywords: Wnt11
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Journal: Development
Development (2022) 149 (17): dev200552.
Published: 8 September 2022
...., 2012 ). We designed guide RNAs targeting the first two exons of wnt11b.L on chromosome 8L (hereafter wnt11b ) ( Fig. S1A ; Table S1 ). These guides lack homology to the paralogous wnt11.L/S genes ( wnt11-r ), which are located on chromosomes 2L/2S and are not expressed maternally, but have...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (22): dev199825.
Published: 26 November 2021
.... Specifically, WNT11 is highly expressed, as confirmed by RNA in situ hybridization, leading us to hypothesize that cecal expression of WNT11 is important for ENCC colonization of the hindgut. Organ cultures using embryonic day 6 avian intestine show that WNT11 inhibits enteric neuronal differentiation...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (5): 1023–1033.
Published: 1 March 2012
... Muscle specific kinase MuSK Unplugged Wnt11 Dishevelled Rab11 Recycling endosome Neuromuscular junction Planar cell polarity AChR pre-pattern Motor axons Synapse formation requires the precise alignment of pre- and postsynaptic elements. In the case of neuromuscular...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (6): 1161–1172.
Published: 15 March 2011
... previously reported for loss of Wnt11. In cell culture, Fz4 and Fz8 can mediate noncanonical signaling stimulated by Wnt11, but only Fz4 mediates Wnt11-stimulated canonical signaling. In genetically mosaic mouse ureteric buds, competition between phenotypically mutant Fz4 −/− or Fz4 −/− ;Fz8 −/− cells...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (24): 4083–4088.
Published: 15 December 2009
... and Crescent (Cres), which are members of the sFRP family, have the ability to regulate the diffusibility and signalling areas of the Wnt ligands Wnt8 and Wnt11. We found, using the Xenopus embryo, that Wnts do not diffuse effectively, whereas Frzb and Cres spread very widely. Interestingly, Frzb and Cres...
Includes: Supplementary data
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Journal Articles
Journal: Development
Development (2005) 132 (11): 2587–2597.
Published: 1 June 2005
... show that Wnt11 is expressed in tissue adjacent to neural crest cells expressing the Wnt receptor Frizzled7 ( Fz7 ). Furthermore, loss- and gain-of-function experiments reveal that Wnt11 plays an essential role in neural crest migration. Inhibition of neural crest migration by blocking Wnt11 activity...
Journal Articles
Journal Articles
Journal: Development
Development (2003) 130 (14): 3175–3185.
Published: 15 July 2003
... of the Wolffian duct derived ureteric bud is integral in the generation of ureteric tips and the elaboration of the collecting duct system. Wnt11, a member of the Wnt superfamily of secreted glycoproteins, which have important regulatory functions during vertebrate embryonic development, is specifically expressed...
Journal Articles
Journal: Development
Development (2002) 129 (20): 4763–4772.
Published: 15 October 2002
... and specification of dermal progenitors from the medial dermomyotome. This comprises two distinct domains: the dorsomedial lip and a more central region (or intervening zone) that derives from it. We confirm that Wnt1 induces Wnt11 expression in the dorsomedial lip as previously shown, and show using DiI injections...