... knot (kn) Hh signalling EGF-receptor Drosophila wing vein The organization of the Drosophila wing veins is a simple system in which to study developmental patterning. The venation pattern consists primarily of five longitudinal veins (thickened cuticular regions providing structural...

...Hitoshi Matakatsu; Ryosuke Tadokoro; Sumiko Gamo; Shigeo Hayashi The wing of Drosophila is separated into several sectors by the wing veins. Vein primordia are specified by the positional information provided by hedgehog and decapentaplegic in the wing imaginal disc and express the key regulatory...

... 9 1998 © 1998 by Company of Biologists 1998 Drosophila Wing vein Paravein Boundaries Lateral inhibition rhomboid hedgehog Wing vein development in Drosophila can be separated into two temporally distinct periods: an initiation phase, which takes place during...

... of segmentation genes within the abdominal region of the embryo. In this study, we present evidence that kni and knrl link A/P positional information in larval wing imaginal discs to morphogenesis of the second longitudinal wing vein (L2). We show that kni and knrl are expressed in similar narrow stripes...

... are reversed, and vein loss occurs because central provein cells are unable to stably adopt the vein cell fate. Our findings imply that Delta-Notch signalling exerts feedback regulation on Delta and Notch expression during metamorphic wing vein development, and that the resultant asymmetries in Delta and Notch...

... that Dpp organizes the patterning of the entire wing disc. We have tested this proposal by studying the response to distinct levels of ectopic expression of Hh and Dpp, using the sensory organ precursors (SOPs) of the wing and notum and the presumptive wing veins as positional markers. Here, we show...

... of a boundary by the maternal Bicoid morphogen gradient in the blastoderm embryo. * Author for correspondence 02 10 1996 © 1997 by Company of Biologists 1997 wing vein boundary pattern formation imaginal disc rhomboid spalt decapentaplegic Drosophila engrailed...

... vein primordia mediates the localized formation of wing veins. In this paper we investigate the genetic hierarchy guiding vein development, by testing for genetic interactions between rho alleles and a wide variety of wing vein mutations and by examining the pattern of rho expression in mutant...