... clones are cell-autonomous, consistent with a morphogen function. Shifts in expression of WntA and fz2 in WntA crispant pupae show that they are under positive and negative feedback, respectively. Fz1 is required for Wnt-independent planar cell polarity in the wing epithelium. Fz3 and Fz4 show phenotypes...

.... In the Drosophila wing epithelium, an extracellular gradient of the Wnt1 homolog Wingless (Wg) was observed extending over several cells away from producing cells. Surprisingly, however, it was also shown that a membrane-tethered Neurotactin-Wg fusion protein (NRT-Wg) can largely replace endogenous Wg, leading...

...). In invertebrates, epithelial junctional complexes are composed of two types of junctions, the adherens junctions and the septate junctions(Muller, 2000 ; Tepass et al., 2001). Drosophila PVR PVF VEGF PDGF Epithelial polarity Wing epithelium Actin organization © 2004. 2004 14 1 2004...