... segments of insects, has no effect on wing development. This view has been obtained from studies in two main model species: Drosophila and Tribolium. Here, we show that partial loss of function of Antp resulted in reduced and malformed adult wings in Bombyx , Drosophila and Tribolium . Antp mediates wing...

... survival signal Wing development dMyc (Dm)-induced cell competition dNAB ( Drosophila Nab) A fundamental question in development is how growth, cell fate specification and pattern formation are spatially and temporally coordinated to control the final shape, size and cellular make-up...

... pathway is required many times during normal wing development. Especially notable is the role of Notch activation in restricting the width of the wing veins within a pro-vein territory( de Celis, 2003 ; Huppert et al., 1997 ). Utilizing the UAS-GAL4 system, dsRNA constructs of Drosophila ADAM...

... to establish a Wingless-dependent organizer at the dorsal/ventral compartment boundary of the Drosophila wing. Development 121 , 4215 -4225. Freeman, M. ( 2000 ). Feedback control of intercellular signalling in development. Nature 408 , 313 -319. Gerlitz, O. and Basler, K. ( 2002 ). Wingful...

...Shian-Jang Yan; Yi Gu; Willis X. Li; Robert J. Fleming Drosophila wing development is a useful model to study organogenesis, which requires the input of selector genes that specify the identity of various morphogenetic fields (Weatherbee, S. D. and Carroll, S. B.(1999) Cell 97, 283-286) and cell...

... 2003 © 2003. 2003 LIM domain Homeodomain Drosophila Wing development Apterous Chip A diverse set of developmental programs in animals are controlled by members of the LIM-homeodomain (LIM-HD) family of transcription factors. These programs include, among others, early...

...L. Alberto Baena-López; Antonio García-Bellido The gene vestigial has been proposed to act as a master gene because of its supposed capacity to initiate and drive wing development. We show that the ectopic expression of vestigial only induces ectopic outgrowths with wing cuticular differentiation...

...Ulrich Weihe; Marco Milán; Stephen M. Cohen Apterous is a LIM-homeodomain protein that confers dorsal compartment identity in Drosophila wing development. Apterous activity requires formation of a complex with a co-factor, Chip/dLDB. Apterous activity is regulated during wing development by dLMO...

... experimentally; however, loss of function analysis indicates that they have different functions during development and analysis of their signalling during wing development indicates that the Fringe protein can discriminate between the two ligands. This raises the possibility that the signalling of Delta...

... these homologous signals from activating their receptor(s). In this study, we investigate the functions of various forms of the Drosophila Sog protein using the discriminating assay of Drosophila wing development. We find that misexpression of Drosophila Sog, or its vertebrate counterpart Chordin, generates a very...

... Wing development Wing hinge homothorax wingless Notch vestigial Drosophila extradenticle The wing imaginal disc of Drosophila gives rise to the mesonotum, the major portion of the fly notum, and its associated appendage, the wing ( Bryant, 1978 ). The wing is composed...

.... * Author for correspondence (e-mail: [email protected] ) 14 01 2000 21 02 2000 © 2000 by Company of Biologists 2000 Wing development Notch signalling Abruptex fringe Signalling by the transmembrane receptor Notch (N) influences cell fates in many developmental...

... in the Drosophila wing . Development 124 , 1919 – 1928 . 10.1242/dev.124.10.1919 Delidakis , C. and Artavanis-Tsakonas , S. ( 1992 ). The Enhancer of split [ E(spl) ] locus of Drosophila encodes seven independent helix-loop-helix proteins . Proc. Natl. Acad. Sci. USA 89 , 8731...

... restricts Notch signalling to the dorsoventral boundary of the developing wing blade. Here we report the results of experiments aimed at establishing the relationships between Fringe, Serrate and Delta during wing development. We find that Serrate is not required for the initiation of wing development...

... ; Tabata et al., 1995 ). Drosophila engrailed polyhomeotic Compartment boundary Target gene Wing development © 1998 by Company of Biologists 1998 18 6 1998 9 7 1998 * Author for correspondence (e-mail: [email protected] ) Therefore, the maintenance...

... ) * Present address: Department of Biology, Grinnell College, Grinnell, Iowa 50112, USA 30 03 1998 06 05 1998 © 1998 by Company of Biologists 1998 Notch signaling vestigial wingless Drosophila Wing development Cell proliferation UAS-GAL4 system Multicellular...

... for correspondence (e-mail: [email protected] ) 09 07 1997 © 1997 by Company of Biologists 1997 Additional data support the hypothesis that ligand binding is insufficient for NOTCH activation, or at least for the generation of ligand-specific responses by NOTCH. During wing development...

... of fringe to regulate Serrate without altering Serrate -specific signaling. * Author for correspondence (e-mail: [email protected] ) 21 05 1997 © 1997 by Company of Biologists 1997 Drosophila wing development Serrate fringe Notch activation The Notch...

... in the developing wing disc and the subsequent localized expression of interveinspecific structural genes. * Author for correspondence 03 06 1996 © 1996 by Company of Biologists 1996 DSRF MADS-box blistered Drosophila wing development vein-intervein fate The Drosophila...

...-specific expression of Snail, Vestigial and β-galactosidase regulated by escargot enhancer were found as well as in wild-type embryos. However, in escargot snail double mutant embryos, wing development proceeded until stage 13, but the marker expression was not maintained in later stages...