... oocytes. † Author for correspondence (e-mail: [email protected] ) * Present address: Department of Biology, College of William and Mary,Williamsburg, VA 23187, USA 7 12 2005 © 2006. 2006 Oocyte maturation Meiotic maturation Myt1 Wee1 Cdk1...

...Zhigang Jin; Ellen M. Homola; Philip Goldbach; YunHee Choi; Julie A. Brill; Shelagh D. Campbell The metazoan Wee1-like kinases Wee1 and Myt1 regulate the essential mitotic regulator Cdk1 by inhibitory phosphorylation. This regulatory mechanism, which prevents Cdk1 from triggering premature mitotic...

... for correspondence (e-mail: [email protected] ) * Present address: Abbott Laboratories; Abbott Park, IL 60064, USA 22 12 2003 © 2004. 2004 Xenopus Wee1 Wee2 Cdk Cell cycle Morphogenesis Convergent extension Somitogenesis During embryogenesis, there must...

... mitotic cell cycle, the mid-blastula transition (MBT) and at gastrulation. In this report, we investigate the contribution of maternal Wee1, a kinase inhibitor of CyclinB/Cdc2, to these crucial developmental transitions. By depleting Wee1 protein levels using antisense morpholino oligonucleotides, we show...

...Monica S. Murakami; George F. Vande Woude ABSTRACT In Xenopus , cdc2 tyrosine phosphorylation is detected in the first 60-75 minute cell cycle but not in the next eleven cell cycles (cycles 2-12) which are only 30 minutes long. Here we report that the wee1/cdc25 ratio increases before the first...