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Keywords: Wee1
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Journal Articles
Journal: Development
Development (2006) 133 (4): 697–709.
Published: 15 February 2006
... maturation Myt1 Wee1 Cdk1 Oocyte growth and differentiation (oogenesis) are crucial for fertilization competency and the rapid cell divisions of early embryonic development. The developing oocyte is essentially a synthetic factory and maternal storehouse for the factors required...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (18): 4075–4085.
Published: 15 September 2005
...Zhigang Jin; Ellen M. Homola; Philip Goldbach; YunHee Choi; Julie A. Brill; Shelagh D. Campbell The metazoan Wee1-like kinases Wee1 and Myt1 regulate the essential mitotic regulator Cdk1 by inhibitory phosphorylation. This regulatory mechanism, which prevents Cdk1 from triggering premature mitotic...
Journal Articles
Journal: Development
Development (2004) 131 (8): 1703–1715.
Published: 15 April 2004
... for correspondence (e-mail: pmueller@midway.uchicago.edu ) * Present address: Abbott Laboratories; Abbott Park, IL 60064, USA 22 12 2003 © 2004. 2004 Xenopus Wee1 Wee2 Cdk Cell cycle Morphogenesis Convergent extension Somitogenesis During embryogenesis, there must...
Journal Articles
Journal: Development
Development (2004) 131 (3): 571–580.
Published: 01 February 2004
... mitotic cell cycle, the mid-blastula transition (MBT) and at gastrulation. In this report, we investigate the contribution of maternal Wee1, a kinase inhibitor of CyclinB/Cdc2, to these crucial developmental transitions. By depleting Wee1 protein levels using antisense morpholino oligonucleotides, we show...