... responses that ensure animals develop properly. In water, the nervous system induces an adaptive response that reinforces vulval development through an unknown backup signal for vulval induction. This response involves the heterotrimeric G-protein EGL-30//G αq acting in motor neurons. It also requires body...

... of Biologists Ltd 2013 FGF Wnt C. elegans Vulval development Cell polarity The orientation of asymmetric cell divisions is essential for proper tissue architecture and organogenesis ( Strutt, 2005 ). Loss of cell polarity and asymmetry is a major factor in tumor formation...

... for correspondence (e-mail: [email protected] ) 23 12 2004 ©2005. 2005 LIN-1 SUMO ETS Chromatin Vulval development Transcription Caenorhabditis elegans LIN-1 is a DNA-binding transcription factor that is a member of the Elk subfamily of ETS proteins( Beitel et al., 1995...

... is required maternally, but not zygotically for embryonic development. Our analysis of vulval development in cye-1 mutants suggests that a timing mechanism may control the onset of vulval cell terminal differentiation: once induced, these cells appear to differentiate after a set amount of time, rather than...

... specification during Caenorhabditis elegans vulval development . Curr. Opin. Genet. Dev . 4 , 508 – 516 . 10.1016/0959-437X(94)90065-B Ferguson , E. L. and Horvitz , H. R. ( 1985 ). Identification and genetic characterization of 22 genes that affect the vulval cell lineages...

... of Biologists 1998 Hox genes Ras signaling C. elegans Vulval development lin-39 Two well-conserved strategies for determining patterns of cellular differentiation during development are the use of Ras-mediated intercellular signals to specify particular cell fates and the use of homeotic...