... with a significant decrease in retinoic acid synthesis by lens-removed eyes. Restoring retinoic acid signalling in lens-removed eyes by implanting beads soaked in retinoic acid or retinal, but not vitamin A, rescued eye size. Conversely, blocking retinoic acid synthesis decreased eye size in lens-containing eyes...

... ) * Present address: EMBL, Meyerhofstrasse 1, D-69117 Heidelberg, Germany 11 7 2005 ©2005. 2005 Axolotl Retinoic acid Vitamin A Homeobox How cells interpret their position along the three axes of a morphogenetic field is fundamental to the correct patterning of developing...

... (provitamins) of vitamin A, which is indispensable for chordate development. As egg yolk also contains stored vitamin A, carotenoids have so far been solely discussed as pigments for the coloration of the offspring. Based on our recent molecular identification of the enzyme catalyzing provitamin A conversion...

... of this territory. *Author for correspondence (e-mail: [email protected] ) 13 3 2001 © 2001. 2001 Nuclear receptors Rhombomeres Hox genes kreisler Embryo culture Mouse Vitamin A Retinoic acid (RA), a hormonal signal derived from vitamin A (retinol), is essential...

... ) 30 11 1998 21 August 1998 © 1998 by Company of Biologists 1998 Vitamin A Retinoid Retinoic acid Chick Many different vertebrate embryos at many different stages of development have been used to examine the effects of exogenous retinoids. Gastrulation, neural patterning...

...Jesús M. Grondona; Philippe Kastner; Anne Gansmuller; Didier Décimo; Pierre Chambon; Manuel Mark ABSTRACT The eye is the organ whose development is the most frequently altered in response to maternal vitamin A deficiency [VAD; Warkany, J. and Schraffenberger, S. (1946). Archs Ophthalmol . 35, 150...

... embryogenesis . Development 115 , 973 – 987 . 10.1242/dev.115.4.973 Sucov , H. M. , Dyson , E. , Gumeringer , C. L. , Price , J. , Chien , K. R. and Evans , R. M. ( 1994 ). RXRα mutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis...

... and CRABPII double mutant vitamin A gene targeting Vitamin A (retinol), an essential component of the diet, is indispensable for normal growth, vision, maintenance of numerous tissues, reproduction and overall survival ( Wolbach and Howe, 1925 ; for reviews see Sporn et al., 1994 , and Blomhoff...

... unilateral clefting vitamin A cleft palate craniofacial malformation teratogen Comments focussed primarily on the differential teratogenicity of the various retinoids used experimentally and on the dose levels concerned. Dr Johnston raised the issue of retinoid blood levels following application...

...Nigel Stephens; Nigel Holder ABSTRACT The innervation of the biceps muscle was examined in regenerated and vitamin A-induced serially duplicated axolotl forelimbs using retrograde transport of horseradish peroxidase. The regenerated biceps muscle becomes innervated by motor neurones in the same...

...S. R. Scadding; M. Maden ABSTRACT Vitamin A can have different effects on developing and regenerating limbs depending on the mode of administration. Previous work has demonstrated the differential effect of retinol palmitate on limb development and regeneration in Xenopus laevis . The purpose...

...S. R. Scadding; M. Maden ABSTRACT The purpose of these experiments was to compare the effects of vitamin A on developing and regenerating limbs in Xenopus laevis tadpoles. Each tadpole had one hindlimb amputated to induce regeneration while the contralateral developing limb was left intact...

...S. R. Scadding; M. Maden ABSTRACT The objective of this investigation was to compare the effect of vitamin A on limb development and limb regeneration in the same animal, at the same time, thus eliminating the possibility that species differences or different rates of uptake between animals would...