.... Published by The Company of Biologists Ltd 2021 Summary: This study describes the first visualization of a topographic map forming and maturing in a living animal and identifies the adhesion molecule Contactin 2 as a key regulator in that process. Visual system Zebrafish Axon guidance...

... of the visual scene. However, in the developing visual system, RGC interactions extend beyond their synaptic partners such that they guide development before the onset of vision. In this Review, we summarize our current understanding of how interactions between RGCs and their environment influence cellular...

...Kristen M. Koenig; Jeffrey M. Gross ABSTRACT For centuries, the eye has fascinated scientists and philosophers alike, and as a result the visual system has always been at the forefront of integrating cutting-edge technology in research. We are again at a turning point at which technical advances...

... of the Drosophila visual system , the ocellar retina, we have discovered that ocellar cells use the non-linear gradient of Hh as a temporal cue, collectively performing the biological equivalent of a mathematical logarithmic transformation. In this way, a morphogen diffusing from a non-moving source is decoded...

...Holger Apitz; Iris Salecker Differences in neuroepithelial patterning and neurogenesis modes contribute to area-specific diversifications of neural circuits. In the Drosophila visual system, two neuroepithelia, the outer (OPC) and inner (IPC) proliferation centers, generate neuron subtypes for four...

... axons. The data reveal a novel mechanism for regulation of the interaction between axons and neuronal cell bodies that establishes precise neuronal networks. * Author for correspondence (e-mail: [email protected] ) 15 12 2005 © 2006. 2006 Visual system Lamina...

...Shoko Yoshida; Laurent Soustelle; Angela Giangrande; Daiki Umetsu; Satoshi Murakami; Tetsuo Yasugi; Takeshi Awasaki; Kei Ito; Makoto Sato; Tetsuya Tabata The Drosophila visual system consists of the compound eyes and the optic ganglia in the brain. Among the eight photoreceptor (R) neurons, axons...

...Jasmine D'Souza; Michael Hendricks; Sylvie Le Guyader; Sivan Subburaju; Barbara Grunewald; Klaus Scholich; Suresh Jesuthasan Visual system development is dependent on correct interpretation of cues that direct growth cone migration and axon branching. Mutations in the zebrafish esrom gene disrupt...

... conserved inhibitory responses in the presence of co-impinging signals from multiple families of guidance molecules. * Author for correspondence (e-mail: [email protected] ) 20 11 2002 © 2003. 2003 Visual system Retinal ganglion cell Pathfinding Semaphorin Growth cone Mouse...

...Karin Dumstrei; Fay Wang; Diana Shy; Ulrich Tepass; Volker Hartenstein Dynamically regulated cell adhesion plays an important role during animal morphogenesis. Here we use the formation of the visual system in Drosophila embryos as a model system to investigate the function of the Drosophila...

... lacking bks function in the eye, R1-R6 axons project through the lamina to terminate in the medulla. Other aspects of visual system development appear completely normal: photoreceptor and lamina cell fates are correctly specified, R7 axons correctly target the medulla, and both correctly targeted R7 axons...

... Eph receptors Ephrins Axon guidance Growth cones Retinal ganglion cells Tyrosine kinase Visual system EphB receptors have been shown to be required for the formation of specific commissures in the CNS. Targeted null mutation of EphB2 ( Nuk ) resulted in a loss of the posterior tract...

...Timothy P. Newsome; Bengt Åsling; Barry J. Dickson ABSTRACT During development of the adult Drosophila visual system, axons of the eight photoreceptors in each ommatidium fasciculate together and project as a single bundle towards the optic lobes of the brain. Within the brain, individual...

... and differentiation of ventral midline cells. The results reported here indicate that EGFR signaling is also required in a narrow medial domain of the head ectoderm (called ‘head midline’ in the following) that includes the anlagen of the medial brain, the visual system (optic lobe, larval eye) and the stomatogastric...

... , 191 – 203 . 10.1242/dev.123.1.191 Holt , C. E. and Harris , W. A. ( 1993 ). Position, guidance and mapping in the developing visual system . J. Neurobiol . 24 , 1400 – 1422 . 10.1002/neu.480241011 Hope , R. A. , Hammond , B. J. and Gaze , R. M. ( 1976...

...-mail: [email protected] ) † Boehringer Mannheim, Abteilung TB-DV, Nonnenwald 2, D-82377 Penzberg, Germany 09 04 1996 © 1996 by Company of Biologists 1996 zebrafish Danio rerio mutant screen visual system brain map neuronal specificity During development...

... guidance in the chick visual system: posterior tectal membranes induce collapse of growth cones from the temporal retina . Neuron 2 , 31 – 37 . 10.1016/0896-6273(90)90441-H Currie , J. and Cowan , W. M. ( 1974 ). Some observations on the early development of the optic tectum...

... . A Laboratory Handbook . Cold Spring Harbor, New York : Cold Spring Harbor Laboratory . Banerjee , U. and Zipursky , S. L. ( 1990 ). The role of cell-cell interaction in the development of the Drosophila visual system . Neuron 4 , 177 – 187 . 10.1016/0896-6273(90)90093-U...

... studies with the disconnected (disco) mutation demonstrate that survival of R-cells does not depend on the genotype of the eye, but is correlated with the presence of connections to the optic ganglia. These results suggest the existence of retrograde interactions in the Drosophila visual system...

... to the laterality of its projection arises later. 12 08 1987 © 1987 by Company of Biologists 1987 mouse visual system fluorescent carbocyanine dyes intramembranous diffusion Several different methods have been used to identify and visualize neurones and glia and the details...