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Keywords: Venous valves
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Journal Articles

RASA1-driven cellular export of collagen IV is required for the development of lymphovenous and venous valves in mice

Di Chen, Xin Geng, Philip E. Lapinski, Michael J. Davis, R. Sathish Srinivasan, Philip D. King
Journal: Development
Development (2020) 147 (23): dev192351.
https://doi.org/10.1242/dev.192351
Published: 7 December 2020
... and maintenance of lymphovenous valves (LVV) and venous valves (VV) is unknown. In this study, we show that induced disruption of Rasa1 in mouse embryos did not affect initial specification of LVV or central VV, but did affect their continued development. Similarly, a switch to expression of a catalytically...
View article titled, RASA1-driven cellular export of collagen IV is required for the development of lymphovenous and <span class="search-highlight">venous</span> <span class="search-highlight">valves</span> in mice
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Includes: Supplementary data