... aorta through the maintenance of the Notch pathway. Zebrafish embryo Vascular development Endothelial cells Artery specification Akt and Notch signaling Single cell RNA sequencing National Institutes of Health http://dx.doi.org/10.13039/100000002 R01DK118728-01 R35 HL139945 R01...

... in the vegetative apex, we applied a pipeline for interspecific single-cell gene expression data integration. We contrasted the developmental trajectories of primary phloem and xylem formation in both species, establishing the first comparison of vascular development between a model annual herbaceous and a woody...

... The authors declare no competing or financial interests. 13 9 2021 25 10 2021 © 2021. Published by The Company of Biologists Ltd 2021 Summary: An integrated molecular analysis in zebrafish identifies new molecular markers for pericytes. Pericyte Vascular development...

... their implications for understanding the development of the lymphatic vasculature and the aetiology of lymphatic vascular diseases. Lymphatic Lymphangiogenesis Vascular development Valve development Endothelial cell heterogeneity Vascular malformations Lymphoedema Lymphatic vessels...

... and MAX2 that appear to depend on the developmental context and do not all involve the direct regulation of MAX2 by REV. Shade avoidance Shoot branching Senescence Vascular development HD-ZIPIII Arabidopsis Plant development is highly plastic, and both leaf form and plant stature...

... expression modulator, via interactions with auxin response factors. Arabidopsis Vascular development Auxin Embryo Gene regulatory network Nederlandse Organisatie voor Wetenschappelijk Onderzoek 10.13039/501100003246 NWO; 831.14.003 VICI 865.14.001 European Molecular...

... SAGA Placenta Vascular development TGFβ signaling RTK receptors Endothelial cells Pericytes Mouse National Institutes of Health 10.13039/100000002 R01GM096472 R01HD094400 Cancer Prevention and Research Institute of Texas RP170067 Development of the mouse...

... that endothelial PKA activity is essential for vascular development, specifically regulating the transition from sprouting to stabilization of nascent vessels. Inhibition of endothelial PKA by endothelial cell-specific expression of dominant-negative PKA in mice led to perturbed vascular development, hemorrhage...

... regulates Notch target gene expression during vascular smooth muscle differentiation from neural crest. Notch signaling Hippo signaling Yap Taz Jagged1 Vascular development Neural crest Mouse The neural crest is a transient, migratory, multipotent cell population that contributes...

... of a Sox7 mutant model is still lacking. In this study we generated zebrafish sox7 mutants to understand the role of Sox7 during vascular development. By in vivo imaging of transgenic zebrafish lines we show that sox7 mutants display a short circulatory loop around the heart as a result of aberrant...

... Histone methylation Vascular development Vascular stability Endothelium Extracellular matrix Mmp9 Mouse Stability of the vasculature is essential for embryonic development and tissue homeostasis. Although the establishment of vascular cell fate, differentiation, and new vessel formation has...

...Henrik Lindskog; Yung Hae Kim; Eric B. Jelin; Yupeng Kong; Salvador Guevara-Gallardo; Tyson N. Kim; Rong A. Wang Coordinated arterial-venous differentiation is crucial for vascular development and function. The origin of the cardinal vein (CV) in mammals is unknown, while conflicting theories have...

... interests statement The authors declare no competing financial interests. 10 5 2013 © 2013. Published by The Company of Biologists Ltd 2013 Vascular development Angiogenesis Endothelial cells Notch Mouse The vertebrate body contains an extensive tubular system...

... statement The authors declare no competing financial interests. 13 12 2012 © 2013. Published by The Company of Biologists Ltd 2013 Auxin LONESOME HIGHWAY Root Vascular development The vascular bundle is the long-distance transport pathway for water, nutrients and signalling...

... in vascular development. This work provides a resource to allow targeted germline gene inactivation in zebrafish and highlights the benefit of a definitive reverse genetic strategy to reveal gene function. § Authors for correspondence ( [email protected] ; [email protected]...

... 9 2010 © 2010. Lymphangiogenesis Lymphatic vessels Macrophages Vascular development Mouse Lymphatic vessels play crucial roles during embryonic development and adult homeostasis. These specialised vessels uptake, transport and return interstitial fluid and protein...

... of the cell division plane. Despite the fundamental importance of cell division orientation to plant development, the mechanisms regulating this process remain almost completely unknown. During vascular development, the meristematic cambial cells divide down their long axis in a highly orientated manner...

...Stryder M. Meadows; Matthew C. Salanga; Paul A. Krieg The VEGF receptor, FLK1, is essential for differentiation of the endothelial lineage and for embryonic vascular development. Using comparative genomics, we have identified conserved ETS and Krüppel-like factor (KLF)binding sites within the Flk1...

... the blood vessels and are critical for angiogenesis. The de novo differentiation of endothelial cells is known as vasculogenesis, whereas the growth of new blood vessels from pre-existing vessels is known as angiogenesis. To ascertain the function of c-myc in vascular development, we deleted c-myc...

... function in endothelial cells (ECs) in vivo has not been determined because Itgb1 -/- embryos die before vascular development. Excision of Itgb1 from ECs and a subset of hematopoietic cells, using Tie2-Cre , resulted in abnormal vascular development by embryonic day(e) 8.5 and lethality by e10.5. Tie1-Cre...