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Keywords: Vascular development
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Journal Articles
Journal: Development
Development (2022) 149 (21): dev200632.
Published: 17 October 2022
... in the vegetative apex, we applied a pipeline for interspecific single-cell gene expression data integration. We contrasted the developmental trajectories of primary phloem and xylem formation in both species, establishing the first comparison of vascular development between a model annual herbaceous and a woody...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (23): dev200189.
Published: 7 December 2021
...) Dorsal views, anterior is up. (C,E) Lateral view, dorsal is up, anterior is to the left. (F,G) Ventral views, anterior is up. Scale bars: 50 μm (A-D,F); 25 μm (E,G). The zebrafish has been a valuable model for studying vascular development, providing novel insights into conserved processes...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (11): dev167098.
Published: 3 June 2021
... their implications for understanding the development of the lymphatic vasculature and the aetiology of lymphatic vascular diseases. Lymphatic Lymphangiogenesis Vascular development Valve development Endothelial cell heterogeneity Vascular malformations Lymphoedema Fig. 2. Developmental...
Journal Articles
Journal Articles
In collection:
Plant development
Journal: Development
Development (2020) 147 (8): dev186130.
Published: 20 April 2020
... gene expression modulator, via interactions with auxin response factors. Arabidopsis Vascular development Auxin Embryo Gene regulatory network Vascular tissues play a central role in plant growth and development by providing plants with transport capabilities and structural support...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2016) 143 (19): 3582–3590.
Published: 1 October 2016
... that endothelial PKA activity is essential for vascular development, specifically regulating the transition from sprouting to stabilization of nascent vessels. Inhibition of endothelial PKA by endothelial cell-specific expression of dominant-negative PKA in mice led to perturbed vascular development, hemorrhage...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (17): 2962–2971.
Published: 1 September 2015
... regulates Notch target gene expression during vascular smooth muscle differentiation from neural crest. Notch signaling Hippo signaling Yap Taz Jagged1 Vascular development Neural crest Mouse The neural crest is a transient, migratory, multipotent cell population that contributes...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (9): 1695–1704.
Published: 1 May 2015
... of a Sox7 mutant model is still lacking. In this study we generated zebrafish sox7 mutants to understand the role of Sox7 during vascular development. By in vivo imaging of transgenic zebrafish lines we show that sox7 mutants display a short circulatory loop around the heart as a result of aberrant...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (23): 4610–4617.
Published: 1 December 2014
... Histone methylation Vascular development Vascular stability Endothelium Extracellular matrix Mmp9 Mouse Stability of the vasculature is essential for embryonic development and tissue homeostasis. Although the establishment of vascular cell fate, differentiation, and new vessel formation has...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (5): 1120–1128.
Published: 1 March 2014
...Henrik Lindskog; Yung Hae Kim; Eric B. Jelin; Yupeng Kong; Salvador Guevara-Gallardo; Tyson N. Kim; Rong A. Wang Coordinated arterial-venous differentiation is crucial for vascular development and function. The origin of the cardinal vein (CV) in mammals is unknown, while conflicting theories have...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (14): 3051–3061.
Published: 15 July 2013
... . Copeland N. G. , Jenkins N. A. , Court D. L. ( 2001 ). Recombineering: a powerful new tool for mouse functional genomics . Nat. Rev. Genet. 2 , 769 – 779 . Dorrell M. I. , Aguilar E. , Friedlander M. ( 2002 ). Retinal vascular development is mediated...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (4): 765–769.
Published: 15 February 2013
... . Science 282 , 2226 - 2230 . Hardtke C. S. , Berleth T. ( 1998 ). The Arabidopsis gene MONOPTEROS encodes a transcription factor mediating embryo axis formation and vascular development . EMBO J. 17 , 1405 - 1411 . Hejátko J. , Blilou I. , Brewer P. B. , Friml...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (20): 4555–4564.
Published: 15 October 2011
... in vascular development. This work provides a resource to allow targeted germline gene inactivation in zebrafish and highlights the benefit of a definitive reverse genetic strategy to reveal gene function. § Authors for correspondence ( nathan.lawson@umassmed.edu ; scot.wolfe@umassmed.edu...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (22): 3899–3910.
Published: 15 November 2010
... 9 2010 © 2010. Lymphangiogenesis Lymphatic vessels Macrophages Vascular development Mouse Lymphatic vessels play crucial roles during embryonic development and adult homeostasis. These specialised vessels uptake, transport and return interstitial fluid and protein...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (5): 767–774.
Published: 1 March 2010
... of the cell division plane. Despite the fundamental importance of cell division orientation to plant development, the mechanisms regulating this process remain almost completely unknown. During vascular development, the meristematic cambial cells divide down their long axis in a highly orientated manner...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2008) 135 (14): 2467–2477.
Published: 15 July 2008
... the blood vessels and are critical for angiogenesis. The de novo differentiation of endothelial cells is known as vasculogenesis, whereas the growth of new blood vessels from pre-existing vessels is known as angiogenesis. To ascertain the function of c-myc in vascular development, we deleted c-myc...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (12): 2193–2202.
Published: 15 June 2008
... function in endothelial cells (ECs) in vivo has not been determined because Itgb1 -/- embryos die before vascular development. Excision of Itgb1 from ECs and a subset of hematopoietic cells, using Tie2-Cre , resulted in abnormal vascular development by embryonic day(e) 8.5 and lethality by e10.5. Tie1-Cre...
Includes: Multimedia, Supplementary data
Journal Articles