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Keywords: Unc-5
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Journal Articles
Journal: Development
Development (2014) 141 (22): 4395–4405.
Published: 15 November 2014
... protrusion and that repulsive UNC-40–UNC-5 heterodimers inhibit filopodial protrusion in C. elegans . Here, we identify cytoplasmic signaling molecules required for UNC-6-mediated inhibition of filopodial protrusion involved in axon repulsion. We show that the Rac-like GTPases CED-10 and MIG-2, the Rac GTP...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (10): 1798–1805.
Published: 15 May 2012
... both Grn and Eve are in the same pathway as Unc-5 in dorsal motoneurons (dMNs). In grn mutants, in which dMNs fail to reach their muscle targets, dMNs show significantly reduced levels of unc-5 mRNA expression and this phenotype can be partially rescued by the reintroduction of unc-5 . We also show...
Includes: Supplementary data