1-3 of 3
Keywords: UHRF1
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Uhrf1 is indispensable for normal limb growth by regulating chondrocyte differentiation through specific gene expression

Available to Purchase
Michiko Yamashita, Kazuki Inoue, Noritaka Saeki, Maky Ideta-Otsuka, Yuta Yanagihara, Yuichiro Sawada, Iori Sakakibara, Jiwon Lee, Koichi Ichikawa, Yoshiaki Kamei, Tadahiro Iimura, Katsuhide Igarashi, Yasutsugu Takada, Yuuki Imai
Journal: Development
Development (2018) 145 (1): dev157412.
https://doi.org/10.1242/dev.157412
Published: 8 January 2018
... by epigenetic regulators. Among these, ubiquitin-like with PHD and RING finger domains 1 (Uhrf1) is reported to have diverse epigenetic functions, including regulation of DNA methylation. However, the physiological functions of Uhrf1 in skeletal tissues remain unclear. Here, we show that limb mesenchymal cell...
View articletitled, Uhrf1 is indispensable for normal limb growth by regulating chondrocyte differentiation through specific gene expression
Open the PDF for Uhrf1 is indispensable for normal limb growth by regulating chondrocyte differentiation through specific gene expression in another window
Includes: Supplementary data
Journal Articles

Loss of DNA methylation in zebrafish embryos activates retrotransposons to trigger antiviral signaling

Available to Purchase
Yelena Chernyavskaya, Raksha Mudbhary, Chi Zhang, Debra Tokarz, Vinitha Jacob, Smita Gopinath, Xiaochen Sun, Shuang Wang, Elena Magnani, Bhavani P. Madakashira, Jeffrey A. Yoder, Yujin Hoshida, Kirsten C. Sadler
Journal: Development
Development (2017) 144 (16): 2925–2939.
https://doi.org/10.1242/dev.147629
Published: 15 August 2017
... based on a lack of methylation and initiate an immune response to clear the infection. Zebrafish embryos with global DNA hypomethylation caused by mutations in the u biquitin-like with PHD and ring finger domains 1 ( uhrf1 ) or DNA methyltransferase 1 ( dnmt1 ) genes exhibit a robust interferon...
View articletitled, Loss of DNA methylation in zebrafish embryos activates retrotransposons to trigger antiviral signaling
Open the PDF for Loss of DNA methylation in zebrafish embryos activates retrotransposons to trigger antiviral signaling in another window
Includes: Supplementary data
Journal Articles

DNA hypomethylation induces a DNA replication-associated cell cycle arrest to block hepatic outgrowth in uhrf1 mutant zebrafish embryos

Available to Purchase
Vinitha Jacob, Yelena Chernyavskaya, Xintong Chen, Poh Seng Tan, Brandon Kent, Yujin Hoshida, Kirsten C. Sadler
Journal: Development
Development (2015) 142 (3): 510–521.
https://doi.org/10.1242/dev.115980
Published: 1 February 2015
...Vinitha Jacob; Yelena Chernyavskaya; Xintong Chen; Poh Seng Tan; Brandon Kent; Yujin Hoshida; Kirsten C. Sadler UHRF1 (ubiquitin-like, containing PHD and RING finger domains, 1) recruits DNMT1 to hemimethylated DNA during replication and is essential for maintaining DNA methylation. uhrf1 mutant...
View articletitled, DNA hypomethylation induces a DNA replication-associated cell cycle arrest to block hepatic outgrowth in uhrf1 mutant zebrafish embryos
Open the PDF for DNA hypomethylation induces a DNA replication-associated cell cycle arrest to block hepatic outgrowth in uhrf1 mutant zebrafish embryos in another window
Includes: Supplementary data